ID   HSP7X_PIG               Reviewed;         379 AA.
AC   P34934;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Heat shock 70 kDa protein;
DE   Flags: Fragment;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Liver;
RX   PubMed=1697703;
RA   Buchman T.G., Cabin D.E., Vickers S., Deutschman C.S., Delgado E.,
RA   Sussman M.M., Bulkley G.B.;
RT   "Molecular biology of circulatory shock. Part II. Expression of four groups
RT   of hepatic genes is enhanced after resuscitation from cardiogenic shock.";
RL   Surgery 108:559-566(1990).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; M29506; AAA02938.1; -; mRNA.
DR   PIR; I46588; I46588.
DR   AlphaFoldDB; P34934; -.
DR   SMR; P34934; -.
DR   PeptideAtlas; P34934; -.
DR   PRIDE; P34934; -.
DR   Proteomes; UP000008227; Unplaced.
DR   Proteomes; UP000314985; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0031072; F:heat shock protein binding; IBA:GO_Central.
DR   GO; GO:0051787; F:misfolded protein binding; IBA:GO_Central.
DR   GO; GO:0044183; F:protein folding chaperone; IBA:GO_Central.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0034620; P:cellular response to unfolded protein; IBA:GO_Central.
DR   GO; GO:0051085; P:chaperone cofactor-dependent protein refolding; IBA:GO_Central.
DR   GO; GO:0042026; P:protein refolding; IBA:GO_Central.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Nucleotide-binding; Reference proteome; Stress response.
FT   CHAIN           <1..379
FT                   /note="Heat shock 70 kDa protein"
FT                   /id="PRO_0000078286"
FT   NON_TER         1
SQ   SEQUENCE   379 AA;  42290 MW;  E5F9DBB9BD47AB6F CRC64;
     RRLRTACERA KRTLSSSTQA TLEIDSLFEG VDFYTSITRA RFEELCSDLF RSTLEPVEKA
     LRDAKLDKAQ IHDIVLVGGS TRIPKIQKLL QDFFNGRELN KSINPDEAVA YGAAVQAAVL
     MGDKCEKVQD LLLLDVAPLS LGLETAGGVM TTLIQRNATI PTKQTQNFHY LLQNNQPGVL
     IQVYEGERAM TRDNNLLGRF ELSRIPPTPR GVPQIEVTFD IDANGILSVT ATDRSTGRAN
     KMTLTSDKGR LSKEEVERMV REAASHKVED EAQRDRVAAK NSLEAYVFHV KGSLHEESLR
     DKIPEEDRCK VQDKCQEVPY LWLEHNQLAE KEEYEHQKRE LEQIASISQL LGPCTWGSSC
     GAQAPKGGPS TGPVIEEVD