ID   HSP97_MESFR             Reviewed;         886 AA.
AC   Q94738;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=97 kDa heat shock protein;
DE   AltName: Full=Heat shock protein 110;
GN   Name=HSP110;
OS   Mesocentrotus franciscanus (Giant red sea urchin) (Strongylocentrotus
OS   franciscanus).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Mesocentrotus.
OX   NCBI_TaxID=1328066;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=9142981; DOI=10.1006/dbio.1997.8512;
RA   Mauk R., Jaworski D., Kamei N., Glabe C.G.;
RT   "Identification of a 97-kDa heat shock protein from S. franciscanus ovaries
RT   with 94% amino acid identity to the S. purpuratus egg surface receptor for
RT   sperm.";
RL   Dev. Biol. 184:31-37(1997).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; U69254; AAB09038.1; -; mRNA.
DR   AlphaFoldDB; Q94738; -.
DR   SMR; Q94738; -.
DR   PRIDE; Q94738; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   Pfam; PF00012; HSP70; 2.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 2.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cytoplasm; Nucleotide-binding.
FT   CHAIN           1..886
FT                   /note="97 kDa heat shock protein"
FT                   /id="PRO_0000078674"
FT   REGION          501..614
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          775..795
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          813..886
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        520..534
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        546..586
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        596..611
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        866..880
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   886 AA;  98447 MW;  252177643ECFEDD8 CRC64;
     MSVVGFDVGN LSSYIAVARG GGIETMANEY SDRLTPSVVS FGEKSRTQGH AARSQAITNY
     KNTLSQFKRF IARQFSDPSV QKDAHVVPYK VTQLPNGNVG MQVQYLGETE TFTPEQIYAM
     ILTKLKATAE VNLCRKVVDC VISVPQYYTD LERRGVIHAA EIAGLNCLRV ISDTTAVALA
     YGIYKQDLPT PEEKPRNVVF VDCGHSSLQV SVCAFNKGKL KVLANASDKN LGGRDFDWLL
     AEHFAVDFQT RYKMDVKSNQ RAWLRLMAEC DKTKKLMSAN ATVISMNIEC IMNDRDVSGK
     ISRADFEALA AELLKRVEVP LKSVLEQTKL KPEDIHSIEI VGGSSRIPSI KETIKKVFKK
     ECSTTLNQDE AVARGCALQC AILSPTFRVR DFTVTDLTPY PIELEWKGTE GEDGSMEVSH
     KNHQAPFSKM LTFYRKEPFE LVARYADTNL PLPERRIGRF KINGVFPTAE GESSKIKVKV
     RVDGHGIFKV SSASLIEKLP AQAEDAMEDS SPEENGPSKE EGSGASQSEN DAPMDQSPVE
     GGAGEGEASA DKEEQAENGA KETSKDKDQT SEGSKSDKES KDQNSEGSKS DNGSTETDAK
     ATKKNKKTIK THELTITAST DELSIAEVNN FFEKEGKMIA QDRLEKEKND AKNAVEEYVY
     DMREKLCDKF EQYVSEKERG SFSKLLEETE NWLYEDGEDE TKSVYQAKIT SLKKIGDPIE
     NRYKEKHERP VAFEELGKAL MLYGKTLDLY SQGDEKYSHI EKDEMAKVEK CLKEKEAWRD
     SKTSAQNQKA AYQDPVVTAQ QIRSEIQSMK FICDPIINKP KPKPKEEPPK DNGPTPAEAA
     KDGGPAPTTE GEEKMDTGDQ APTGEASKEG ETKPDETKPD VEMELD