HSPBB_DANRE
ID HSPBB_DANRE Reviewed; 205 AA.
AC A5JV83; B3DHE3;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 14-OCT-2008, sequence version 2.
DT 03-AUG-2022, entry version 62.
DE RecName: Full=Heat shock protein beta-11;
GN Name=hspb11;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=17888590; DOI=10.1016/j.gene.2007.08.003;
RA Elicker K.S., Hutson L.D.;
RT "Genome-wide analysis and expression profiling of the small heat shock
RT proteins in zebrafish.";
RL Gene 403:60-69(2007).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=18161059; DOI=10.1002/dvdy.21414;
RA Marvin M., O'Rourke D., Kurihara T., Juliano C.E., Harrison K.L.,
RA Hutson L.D.;
RT "Developmental expression patterns of the zebrafish small heat shock
RT proteins.";
RL Dev. Dyn. 237:454-463(2008).
CC -!- TISSUE SPECIFICITY: Expressed specifically in the rostral-most somites
CC at 24 hpf. At 48 hpf, expression continues in the rostral-most somites
CC and also in the notochord. Somite expression was restricted to the
CC vicinity of the horizontal myoseptum. In adults, expressed in the
CC heart. {ECO:0000269|PubMed:17888590, ECO:0000269|PubMed:18161059}.
CC -!- INDUCTION: By heat shock in the somites. {ECO:0000269|PubMed:17888590,
CC ECO:0000269|PubMed:18161059}.
CC -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC {ECO:0000255|PROSITE-ProRule:PRU00285}.
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DR EMBL; EF583631; ABQ57501.1; -; mRNA.
DR EMBL; BC162734; AAI62734.1; -; mRNA.
DR EMBL; BC162749; AAI62749.1; -; mRNA.
DR RefSeq; NP_001092897.1; NM_001099427.1.
DR AlphaFoldDB; A5JV83; -.
DR SMR; A5JV83; -.
DR STRING; 7955.ENSDARP00000026207; -.
DR PaxDb; A5JV83; -.
DR PeptideAtlas; A5JV83; -.
DR GeneID; 796767; -.
DR KEGG; dre:796767; -.
DR CTD; 51668; -.
DR ZFIN; ZDB-GENE-030131-5148; hspb11.
DR eggNOG; KOG3591; Eukaryota.
DR InParanoid; A5JV83; -.
DR OrthoDB; 1187096at2759; -.
DR PhylomeDB; A5JV83; -.
DR TreeFam; TF105049; -.
DR PRO; PR:A5JV83; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0031033; P:myosin filament organization; IMP:ZFIN.
DR GO; GO:0042026; P:protein refolding; IBA:GO_Central.
DR GO; GO:0009408; P:response to heat; IBA:GO_Central.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR InterPro; IPR001436; Alpha-crystallin/sHSP_animal.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR PANTHER; PTHR45640; PTHR45640; 1.
DR Pfam; PF00011; HSP20; 1.
DR SUPFAM; SSF49764; SSF49764; 1.
DR PROSITE; PS01031; SHSP; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Stress response.
FT CHAIN 1..205
FT /note="Heat shock protein beta-11"
FT /id="PRO_0000300628"
FT DOMAIN 67..180
FT /note="sHSP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
FT REGION 184..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 143
FT /note="D -> G (in Ref. 1; ABQ57501)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 205 AA; 23823 MW; E27A4A1CA6B383DA CRC64;
MLCPSTFQPH LSPFMDFHWP VRSLWPETRP LFFQFEQEMM RHMQEMRHNM EFMERLHQRI
FDEIDHVSPM TTFKPISFQL GKEGSHYALT LDTQDFSPEE LAVKQVGRKL RVSGKTEKKQ
DDGKGSYSYR CQEFRQEFDL PEDVNPESVS CSLNNGQLQI QAPREGNTVS NERVIPITYT
PAVKNPALQN SEPENQAVEA EAAEN
