ID   HSPF_DICDI              Reviewed;         233 AA.
AC   Q1ZXL6; Q557H2; Q8T1N9;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Small heat shock protein hspF;
GN   Name=hspF-1; ORFNames=DDB_G0273409;
GN   and
GN   Name=hspF-2; ORFNames=DDB_G0273561;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [3]
RP   INDUCTION [LARGE SCALE ANALYSIS].
RX   PubMed=18559084; DOI=10.1186/1471-2164-9-291;
RA   Sillo A., Bloomfield G., Balest A., Balbo A., Pergolizzi B., Peracino B.,
RA   Skelton J., Ivens A., Bozzaro S.;
RT   "Genome-wide transcriptional changes induced by phagocytosis or growth on
RT   bacteria in Dictyostelium.";
RL   BMC Genomics 9:291-291(2008).
CC   -!- INDUCTION: Up-regulated by phagocytic stimuli.
CC       {ECO:0000269|PubMed:18559084}.
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00285}.
CC   -!- CAUTION: The gene for this protein is duplicated in strains AX3 and
CC       AX4. These strains contain a duplication of a segment of 750 kb of
CC       chromosome 2 compared to the corresponding sequence in strain AX2.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000010; EAL70735.2; -; Genomic_DNA.
DR   EMBL; AAFI02000010; EAS66921.1; -; Genomic_DNA.
DR   RefSeq; XP_001134605.1; XM_001134605.1.
DR   RefSeq; XP_644663.2; XM_639571.2.
DR   AlphaFoldDB; Q1ZXL6; -.
DR   SMR; Q1ZXL6; -.
DR   PaxDb; Q1ZXL6; -.
DR   EnsemblProtists; EAL70735; EAL70735; DDB_G0273561.
DR   EnsemblProtists; EAS66921; EAS66921; DDB_G0273409.
DR   GeneID; 8618952; -.
DR   GeneID; 8619025; -.
DR   KEGG; ddi:DDB_G0273409; -.
DR   KEGG; ddi:DDB_G0273561; -.
DR   dictyBase; DDB_G0273409; hspF-1.
DR   dictyBase; DDB_G0273561; hspF-2.
DR   eggNOG; ENOG502RIH4; Eukaryota.
DR   HOGENOM; CLU_1191751_0_0_1; -.
DR   InParanoid; Q1ZXL6; -.
DR   PRO; PR:Q1ZXL6; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   InterPro; IPR045045; RTM2-like.
DR   PANTHER; PTHR43670; PTHR43670; 1.
DR   Pfam; PF00011; HSP20; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS01031; SHSP; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Stress response.
FT   CHAIN           1..233
FT                   /note="Small heat shock protein hspF"
FT                   /id="PRO_0000363892"
FT   DOMAIN          129..233
FT                   /note="sHSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
SQ   SEQUENCE   233 AA;  27371 MW;  331681DC64A1FCA9 CRC64;
     MTEVTYQIQD QIKQFNNFNP IQKTNYKYQY NSDNENSSLV YLIKNPKQNN FKNYNNKICN
     YKRSLSSSSF QGNEEKETRK KNKAQFYEND FENGFGNISS WLNNSIPYKC EDCNGNNEPP
     HQKLKSQDIP LFTFFEPLTF IHEINKVIHI ELEIAGVDKD DVKVDLTNNI LTIVAKKKSV
     YPLFQNMCEF KRHEKSIGVY KRVLEFNSNT VDKDTIKARY VNGILLITVN KFL