ID   HSPGC_DICDI             Reviewed;         205 AA.
AC   Q76NU5; Q54ZN8;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Small heat shock protein hspG12;
GN   Name=hspG12; ORFNames=DDB_G0277491;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00285}.
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DR   EMBL; AAFI02000020; EAL68708.1; -; Genomic_DNA.
DR   RefSeq; XP_642604.1; XM_637512.1.
DR   AlphaFoldDB; Q76NU5; -.
DR   SMR; Q76NU5; -.
DR   STRING; 44689.DDB0232123; -.
DR   PaxDb; Q76NU5; -.
DR   EnsemblProtists; EAL68708; EAL68708; DDB_G0277491.
DR   GeneID; 8621021; -.
DR   KEGG; ddi:DDB_G0277491; -.
DR   dictyBase; DDB_G0277491; hspG12.
DR   eggNOG; KOG0710; Eukaryota.
DR   HOGENOM; CLU_1328489_0_0_1; -.
DR   InParanoid; Q76NU5; -.
DR   OMA; VINHTEI; -.
DR   PhylomeDB; Q76NU5; -.
DR   PRO; PR:Q76NU5; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   Gene3D; 2.60.40.790; -; 2.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   Pfam; PF00011; HSP20; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS01031; SHSP; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Stress response.
FT   CHAIN           1..205
FT                   /note="Small heat shock protein hspG12"
FT                   /id="PRO_0000363904"
FT   DOMAIN          35..205
FT                   /note="sHSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
FT   REGION          99..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..147
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   205 AA;  23526 MW;  18D4553C797F23E2 CRC64;
     MATIFDILNT LNNNNNNKNY FESCKRQRTN NKTNKTIIDI LPPMDVTMTN DKLIIETELA
     GISKDDIEIS INDSILTIQG EKKKNLNKQL IIEKSSSSPS LLDTKEDEAS IEEFDEDDIK
     PKSTETTSTL SNSKENKKDE NKSKSTEKKF ISERSFGNFK RYLDLTKFLY QLDLNSINTQ
     FENGLLTITI NKKLHYSNTI KININ