ID   HSPI_DICDI              Reviewed;         223 AA.
AC   Q54I91;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Small heat shock protein hspI, mitochondrial;
DE   Flags: Precursor;
GN   Name=hspI; ORFNames=DDB_G0288921;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00285}.
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DR   EMBL; AAFI02000126; EAL62984.1; -; Genomic_DNA.
DR   RefSeq; XP_636488.1; XM_631396.1.
DR   AlphaFoldDB; Q54I91; -.
DR   SMR; Q54I91; -.
DR   PaxDb; Q54I91; -.
DR   EnsemblProtists; EAL62984; EAL62984; DDB_G0288921.
DR   GeneID; 8626871; -.
DR   KEGG; ddi:DDB_G0288921; -.
DR   dictyBase; DDB_G0288921; hspI.
DR   eggNOG; ENOG502RHHV; Eukaryota.
DR   HOGENOM; CLU_1242060_0_0_1; -.
DR   InParanoid; Q54I91; -.
DR   OMA; TSFYRSF; -.
DR   PhylomeDB; Q54I91; -.
DR   PRO; PR:Q54I91; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0043621; F:protein self-association; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0051259; P:protein complex oligomerization; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   GO; GO:0009408; P:response to heat; IBA:GO_Central.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IBA:GO_Central.
DR   GO; GO:0009651; P:response to salt stress; IBA:GO_Central.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   Pfam; PF00011; HSP20; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS01031; SHSP; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; Stress response; Transit peptide.
FT   TRANSIT         1..23
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..223
FT                   /note="Small heat shock protein hspI, mitochondrial"
FT                   /id="PRO_0000363905"
FT   DOMAIN          109..223
FT                   /note="sHSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
SQ   SEQUENCE   223 AA;  25808 MW;  E6CD540D2AFC3627 CRC64;
     MYKLSKTTPF FFRRAFLCGR RGGYPESNLS NFGRPTASTL STSQSSGICE TNDYSNKPYF
     FQVKFEDRFS KKIDKFNECF RHFYYSHGGQ QYMDKFESIF DNWEHEFSKT RGFRSPKTFI
     NESDKGIEIR VELPGFSKEN VKIDFSNGLL NIDALNKNTT IQQPSSNNQQ VESQHQSLME
     FKKSIKLPED IDVSLIKAIM NNGILEISIP KNSYVKSTTI NVQ