ID   HSTN_BOVIN              Reviewed;          58 AA.
AC   C6KGD8;
DT   20-JAN-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Histatherin {ECO:0000303|Ref.1};
DE   Flags: Precursor;
GN   Name=HSTN {ECO:0000303|Ref.1};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000312|Proteomes:UP000009136};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], IDENTIFICATION, AND TISSUE SPECIFICITY.
RA   Glenn M., Grigor M.R., Molenaar A.J., Davis S.R.;
RT   "Compositions Isolated from Bovine Mammary Gland and Methods for their Use;
RT   Patent: US 006833435B2-B 21-DEC-2004.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford;
RX   PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42;
RA   Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., Puiu D.,
RA   Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., Marcais G.,
RA   Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.;
RT   "A whole-genome assembly of the domestic cow, Bos taurus.";
RL   Genome Biol. 10:R42.01-R42.10(2009).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in mammary glands. {ECO:0000305|Ref.1}.
CC   -!- SIMILARITY: Belongs to the histatin/statherin family. {ECO:0000305}.
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DR   EMBL; GQ204113; ACS92704.1; -; mRNA.
DR   EMBL; GQ204115; ACS92706.1; -; mRNA.
DR   EMBL; DAAA02018006; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DAAA02018007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DAAA02018008; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001156886.1; NM_001163414.1.
DR   AlphaFoldDB; C6KGD8; -.
DR   STRING; 9913.ENSBTAP00000054732; -.
DR   PaxDb; C6KGD8; -.
DR   GeneID; 100302500; -.
DR   KEGG; bta:100302500; -.
DR   CTD; 100302500; -.
DR   HOGENOM; CLU_208169_0_0_1; -.
DR   InParanoid; C6KGD8; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:InterPro.
DR   InterPro; IPR030773; Histatin/statherin.
DR   PANTHER; PTHR15057; PTHR15057; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..58
FT                   /note="Histatherin"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5005668772"
SQ   SEQUENCE   58 AA;  7233 MW;  A14ACC7B7EEA8633 CRC64;
     MKIFIFIFIM ALILAMIRAD SSEEKRHRKR KKHHRGYFQQ YQPYQRYPLN YPPAYPFP