ID   HSV2_DEBHA              Reviewed;         432 AA.
AC   Q6BUX9;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=SVP1-like protein 2;
GN   Name=HSV2; OrderedLocusNames=DEHA2C07084g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in mitochondrial or peroxisomal functions and amino
CC       acid signaling pathways. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250}; Peripheral
CC       membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
CC       Note=Vesicular and vacuolar. {ECO:0000250}.
CC   -!- DOMAIN: May contain a beta-propeller domain involved in specific
CC       binding to phosphatidylinositol 3,5-bisphosphate (PIP2), leading to the
CC       association of the protein to the membrane. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat PROPPIN family. {ECO:0000305}.
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DR   EMBL; CR382135; CAG86048.2; -; Genomic_DNA.
DR   RefSeq; XP_457990.2; XM_457990.1.
DR   AlphaFoldDB; Q6BUX9; -.
DR   SMR; Q6BUX9; -.
DR   STRING; 4959.XP_457990.2; -.
DR   EnsemblFungi; CAG86048; CAG86048; DEHA2C07084g.
DR   GeneID; 2900227; -.
DR   KEGG; dha:DEHA2C07084g; -.
DR   VEuPathDB; FungiDB:DEHA2C07084g; -.
DR   eggNOG; KOG2111; Eukaryota.
DR   HOGENOM; CLU_025895_0_1_1; -.
DR   InParanoid; Q6BUX9; -.
DR   OMA; WSFCKFQ; -.
DR   OrthoDB; 966922at2759; -.
DR   Proteomes; UP000000599; Chromosome C.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 3.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Cytoplasmic vesicle; Membrane; Protein transport; Reference proteome;
KW   Repeat; Transport; Vacuole; WD repeat.
FT   CHAIN           1..432
FT                   /note="SVP1-like protein 2"
FT                   /id="PRO_0000051027"
FT   REPEAT          223..263
FT                   /note="WD 1"
FT   REPEAT          268..307
FT                   /note="WD 2"
SQ   SEQUENCE   432 AA;  48200 MW;  5455156091355788 CRC64;
     MNTLSAISNN KQSKELQILN INFNQDQGCF AVGHEYGFLV YNTNPIDIRV KRNFNINGHG
     SGIAHITMLH RTNYLALVGG GKNPKFANNK LVIWDDLKRK NSLNLEFMSP VLNVLLSRIR
     IIVVLKNQVL VYGFSSPPKK FATYETIENE FGLADLSVNF TNSIGNNLST SNSSISSLVS
     NQVSYDSNKY QTLAFPGRSI GQIQIVDVSP SGQEKNLVSI IKAHKSKIRC LALNRSGTLV
     ASASETGTII RVHSTHNTAL LYEFRRGLDR AIVTSMKFSH DDSKLAVLSD KNTLHVYNVS
     PLNTSSGATS DLVTHNETYP VNRSHLLGSI AFPIPIPKYF KSTWSFCSVN TNKYHPSGSD
     NDTINDVGII GWSGNDSIII IWQNKKIWEK YVIVEKRNKY LGDINDGLNT SHQGSSNWEL
     VRFNWKNLDN LD