HSYB_TOBAC
ID HSYB_TOBAC Reviewed; 164 AA.
AC Q93WP7;
DT 05-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 42.
DE RecName: Full=Hydroxyproline-rich systemin B;
DE Contains:
DE RecName: Full=HypSysB I;
DE AltName: Full=TobHypSysB I;
DE Contains:
DE RecName: Full=HypSysB II;
DE AltName: Full=TobHypSysB II;
DE Flags: Precursor;
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000312|EMBL:AAK52097.1};
RN [1] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 36-53, FUNCTION, TISSUE
RP SPECIFICITY, HYDROXYLATION AT PRO-42; PRO-43; PRO-45; PRO-49 AND PRO-50,
RP AND GLYCOSYLATION.
RX PubMed=11459063; DOI=10.1038/35081107;
RA Pearce G., Moura D.S., Stratmann J., Ryan C.A.;
RT "Production of multiple plant hormones from a single polyprotein
RT precursor.";
RL Nature 411:817-820(2001).
RN [2] {ECO:0000305}
RP REVIEW ON FUNCTION.
RX PubMed=12949264; DOI=10.1073/pnas.1934788100;
RA Ryan C.A., Pearce G.;
RT "Systemins: a functionally defined family of peptide signals that regulate
RT defensive genes in Solanaceae species.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:14577-14580(2003).
CC -!- FUNCTION: Activates a lipid-based signal transduction pathway in which
CC linolenic acid is converted to jasmonic acid, a potent activator of
CC defense gene transcription, including proteinase inhibitors.
CC {ECO:0000269|PubMed:11459063}.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed in leaves. {ECO:0000269|PubMed:11459063}.
CC -!- INDUCTION: By methyl jasmonate in leaves.
CC {ECO:0000269|PubMed:11459063}.
CC -!- PTM: O-glycosylated; contains pentose side chains.
CC {ECO:0000269|PubMed:11459063}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY033149; AAK52097.1; -; mRNA.
DR RefSeq; XP_016466072.1; XM_016610586.1.
DR AlphaFoldDB; Q93WP7; -.
DR SMR; Q93WP7; -.
DR GeneID; 107788852; -.
DR KEGG; nta:107788852; -.
DR OrthoDB; 1404983at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IDA:UniProtKB.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Glycoprotein; Hormone; Hydroxylation;
KW Plant defense; Reference proteome; Secreted; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT PROPEP 19..35
FT /evidence="ECO:0000255, ECO:0000269|PubMed:11459063"
FT /id="PRO_0000021461"
FT PEPTIDE 36..53
FT /note="HypSysB I"
FT /evidence="ECO:0000269|PubMed:11459063"
FT /id="PRO_0000021462"
FT PROPEP 54..142
FT /evidence="ECO:0000269|PubMed:11459063"
FT /id="PRO_0000021463"
FT PEPTIDE 143..160
FT /note="HypSysB II"
FT /evidence="ECO:0000250|UniProtKB:Q93WP8"
FT /id="PRO_0000021464"
FT PROPEP 161..164
FT /evidence="ECO:0000250|UniProtKB:Q93WP8"
FT /id="PRO_0000021465"
FT REGION 32..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 42
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:11459063"
FT MOD_RES 43
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:11459063"
FT MOD_RES 45
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:11459063"
FT MOD_RES 49
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:11459063"
FT MOD_RES 50
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000269|PubMed:11459063"
FT MOD_RES 149
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000250"
FT MOD_RES 150
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000250"
FT MOD_RES 152
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000250"
FT CARBOHYD 42
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000255"
FT CARBOHYD 43
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000255"
FT CARBOHYD 45
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000255"
FT CARBOHYD 49
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000255"
FT CARBOHYD 50
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000255"
FT CARBOHYD 149
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000255"
FT CARBOHYD 150
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000255"
FT CARBOHYD 152
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000255"
SQ SEQUENCE 164 AA; 18211 MW; 1F7765E22D0C5F2F CRC64;
MRALFLIYLI LSPFRAVSRT LLENHEGLNV GSGYGRGTNL PPPSPASSPP SKEVSNSVSP
TRTDEKTSEN TELVMTTIAQ GENSNQLFPF LTSSDNYQLA SFKKLSISYL LPVSYVWKLI
SSSSFNHDLV DIFDTSSDEK YWNRKPLSPP SPKPADGHRP LQSY
