ID   HTAXP_HALS3             Reviewed;         406 AA.
AC   B0R4J2;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=HEAT repeat-containing taxis protein OE_2401F;
GN   OrderedLocusNames=OE_2401F;
OS   Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=478009;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=18313895; DOI=10.1016/j.ygeno.2008.01.001;
RA   Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA   Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT   "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT   R1 compared to that of strain NRC-1.";
RL   Genomics 91:335-346(2008).
RN   [2]
RP   FUNCTION, INTERACTION WITH CHE PROTEINS, AND DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=19291314; DOI=10.1186/1471-2180-9-56;
RA   Schlesner M., Miller A., Streif S., Staudinger W.F., Muller J.,
RA   Scheffer B., Siedler F., Oesterhelt D.;
RT   "Identification of Archaea-specific chemotaxis proteins which interact with
RT   the flagellar apparatus.";
RL   BMC Microbiol. 9:56-56(2009).
CC   -!- FUNCTION: Involved in taxis signal transduction. Essential for the
CC       ability to control the direction of flagellar rotation. May have a role
CC       between CheY and the flagellum. {ECO:0000269|PubMed:19291314}.
CC   -!- SUBUNIT: Interacts with chemotaxis (Che) proteins.
CC       {ECO:0000269|PubMed:19291314}.
CC   -!- DISRUPTION PHENOTYPE: Mutants are unable to switch the direction of
CC       flagellar rotation. Flagella rotate only clockwise, resulting in
CC       exclusively forward swimming cells that are unable to respond to tactic
CC       signals. {ECO:0000269|PubMed:19291314}.
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DR   EMBL; AM774415; CAP13657.1; -; Genomic_DNA.
DR   RefSeq; WP_012289252.1; NC_010364.1.
DR   AlphaFoldDB; B0R4J2; -.
DR   SMR; B0R4J2; -.
DR   EnsemblBacteria; CAP13657; CAP13657; OE_2401F.
DR   GeneID; 5953754; -.
DR   GeneID; 62884355; -.
DR   KEGG; hsl:OE_2401F; -.
DR   HOGENOM; CLU_053271_0_0_2; -.
DR   OMA; ALWEIAN; -.
DR   PhylomeDB; B0R4J2; -.
DR   Proteomes; UP000001321; Chromosome.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR004155; PBS_lyase_HEAT.
DR   SMART; SM00567; EZ_HEAT; 8.
DR   SUPFAM; SSF48371; SSF48371; 2.
PE   1: Evidence at protein level;
KW   Chemotaxis; Repeat.
FT   CHAIN           1..406
FT                   /note="HEAT repeat-containing taxis protein OE_2401F"
FT                   /id="PRO_0000429074"
FT   REPEAT          7..41
FT                   /note="HEAT 1"
FT   REPEAT          42..78
FT                   /note="HEAT 2"
FT   REPEAT          90..127
FT                   /note="HEAT 3"
FT   REPEAT          153..184
FT                   /note="HEAT 4"
FT   REPEAT          185..215
FT                   /note="HEAT 5"
FT   REPEAT          216..252
FT                   /note="HEAT 6"
FT   REPEAT          370..406
FT                   /note="HEAT 7"
SQ   SEQUENCE   406 AA;  44197 MW;  208A64378212570E CRC64;
     MPSLYGLERS GDVEKLVELL QESEKETVRR RAAEILGNLD EPEPEGIQAL VDAMSDDDES
     VRAAAIDALT QQEAVDALMR GLDQEVPDSG ATWAQAEAFV ENLESETPEL RMAAANVLGL
     LGVEDTARPL AKQLQTEEHV GVRARVARAL GRIEQPAVTG ILVDCLHGEP LKVRREAAES
     LGRLTTEQAL DGLLSVVEDD SEAMRRTAVS SLGRFETAEP VDALVERLGD ESDLVRRAAV
     FSLIEILSNV PPDQSHELRE TIVDRMSARS DPSIIKSLIE IIDEGTQLHQ RRNATWMLGR
     VAGDQRTKMD AIEALRELLG EDDDLIAQFA ATGLAEIGGA SVETSLLEVV ETQEYGEDAV
     AMAAFALGKV GGDRSRQRLE RLVDETDSEE VRRRAFSAIS KLGGKT