HTF_CRYKY
ID HTF_CRYKY Reviewed; 8 AA.
AC P85575;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 1.
DT 11-DEC-2019, entry version 15.
DE RecName: Full=Hypertrehalosaemic factor {ECO:0000250|UniProtKB:P67790};
DE AltName: Full=Adipokinetic hormone 1 {ECO:0000303|PubMed:19257902};
DE Short=CryKy-AKH-1 {ECO:0000303|PubMed:19257902};
DE AltName: Full=Hypertrehalosaemic neuropeptide {ECO:0000250|UniProtKB:P67790};
OS Cryptocercus kyebangensis (Brown-hooded cockroach).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Cryptocercidae;
OC Cryptocercus.
OX NCBI_TaxID=161578;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AND AMIDATION AT TRP-8.
RC TISSUE=Corpora cardiaca {ECO:0000269|PubMed:19257902};
RX PubMed=19257902; DOI=10.1186/1471-2148-9-50;
RA Roth S., Fromm B., Gaede G., Predel R.;
RT "A proteomic approach for studying insect phylogeny: CAPA peptides of
RT ancient insect taxa (Dictyoptera, Blattoptera) as a test case.";
RL BMC Evol. Biol. 9:50-50(2009).
CC -!- FUNCTION: Hypertrehalosaemic factors are neuropeptides that elevate the
CC level of trehalose in the hemolymph (trehalose is the major
CC carbohydrate in the hemolymph of insects). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the AKH/HRTH/RPCH family. {ECO:0000255}.
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DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR002047; Adipokinetic_hormone_CS.
DR PROSITE; PS00256; AKH; 1.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Hormone; Neuropeptide;
KW Pyrrolidone carboxylic acid; Secreted.
FT PEPTIDE 1..8
FT /note="Hypertrehalosaemic factor"
FT /evidence="ECO:0000269|PubMed:19257902"
FT /id="PRO_0000378639"
FT MOD_RES 1
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000269|PubMed:19257902"
FT MOD_RES 8
FT /note="Tryptophan amide"
FT /evidence="ECO:0000269|PubMed:19257902"
SQ SEQUENCE 8 AA; 1005 MW; 86745775B9C44736 CRC64;
QLNFSPNW