ID   HTPG_CHLPD              Reviewed;         626 AA.
AC   A1BFP7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Chaperone protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=Heat shock protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=High temperature protein G {ECO:0000255|HAMAP-Rule:MF_00505};
GN   Name=htpG {ECO:0000255|HAMAP-Rule:MF_00505};
GN   OrderedLocusNames=Cpha266_1188;
OS   Chlorobium phaeobacteroides (strain DSM 266).
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC   Chlorobium/Pelodictyon group; Chlorobium.
OX   NCBI_TaxID=290317;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 266;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T.,
RA   Overmann J., Bryant D.A., Richardson P.;
RT   "Complete sequence of Chlorobium phaeobacteroides DSM 266.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Molecular chaperone. Has ATPase activity. {ECO:0000255|HAMAP-
CC       Rule:MF_00505}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00505}.
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DR   EMBL; CP000492; ABL65224.1; -; Genomic_DNA.
DR   RefSeq; WP_011745048.1; NC_008639.1.
DR   AlphaFoldDB; A1BFP7; -.
DR   SMR; A1BFP7; -.
DR   STRING; 290317.Cpha266_1188; -.
DR   EnsemblBacteria; ABL65224; ABL65224; Cpha266_1188.
DR   KEGG; cph:Cpha266_1188; -.
DR   eggNOG; COG0326; Bacteria.
DR   HOGENOM; CLU_006684_3_0_10; -.
DR   OMA; MRRMKEM; -.
DR   OrthoDB; 246194at2; -.
DR   Proteomes; UP000008701; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.120.790; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   HAMAP; MF_00505; HSP90; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR037196; HSP90_C.
DR   InterPro; IPR001404; Hsp90_fam.
DR   InterPro; IPR020575; Hsp90_N.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR11528; PTHR11528; 1.
DR   Pfam; PF00183; HSP90; 1.
DR   PIRSF; PIRSF002583; Hsp90; 1.
DR   PRINTS; PR00775; HEATSHOCK90.
DR   SUPFAM; SSF110942; SSF110942; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Reference proteome;
KW   Stress response.
FT   CHAIN           1..626
FT                   /note="Chaperone protein HtpG"
FT                   /id="PRO_1000014909"
FT   REGION          1..332
FT                   /note="A; substrate-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          333..546
FT                   /note="B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          547..626
FT                   /note="C"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
SQ   SEQUENCE   626 AA;  71107 MW;  EAB0C22FCEF6F348 CRC64;
     MTNNDTPGMR EYEYKAEMKQ LLELIVHSLY THPEIFLREL ISNASDALSK VRFNALTDES
     IINSDAGLAI RITLDPEAHT IVIEDNGTGM TEEELILNLG TVARSGTLGF LQALKEQQKE
     LDGNLIGQFG VGFYSVFMVT DEVTVETRSS GADSAGYRWR SGAAGTFTIE RIEKEQRGTK
     ISFALKDEFK EFSEAYRIEQ IIRKYSNFVD FPIFLGDNQI NTISALWQRS KNEVSDEERN
     EFYKFLSNDF NPPLDSLHLS VEGKVCFKAL LFLPEEAPPE LMYRQGDLES RGPQLYVKKV
     LIQQECRDLL PEYLRFVAGV VDTEDLPLNV SREVVQSSKV MANIRQILTG KILSWFESMA
     TDQPEKFRKF YKAFGPFLKI GLNTDFTHRD RIIGLMRFES TKTAEGEYVT FKEYVERMEA
     GQNEIYYHSG SNRIQLLAHP NLEYFQHKGI EVLLLSDPVD VFVIPSIHEY DKKPLKSIEK
     ADIDFTRTGD DKTEPPLPET LSQPLLGLFR QTIGDVIEDV VESHRLVSSP VTLVSGKDSL
     DSSMEKMMKM MHAEMPAAKK ILEVNTSHPI IKNLSGMIMA NEHNPLIRTV IQQLYDGALL
     HEGNLDATTG FLQRMNELIE AATMSR