ID   HTPG_COLP3              Reviewed;         653 AA.
AC   Q47XA7;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Chaperone protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=Heat shock protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=High temperature protein G {ECO:0000255|HAMAP-Rule:MF_00505};
GN   Name=htpG {ECO:0000255|HAMAP-Rule:MF_00505}; OrderedLocusNames=CPS_3901;
OS   Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio
OS   psychroerythus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Colwelliaceae; Colwellia.
OX   NCBI_TaxID=167879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=34H / ATCC BAA-681;
RX   PubMed=16043709; DOI=10.1073/pnas.0504766102;
RA   Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X.,
RA   Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M.,
RA   Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A.,
RA   Zhou L., Davidsen T.M., Wu M., Huston A.L., Lewis M., Weaver B.,
RA   Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.;
RT   "The psychrophilic lifestyle as revealed by the genome sequence of
RT   Colwellia psychrerythraea 34H through genomic and proteomic analyses.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005).
CC   -!- FUNCTION: Molecular chaperone. Has ATPase activity. {ECO:0000255|HAMAP-
CC       Rule:MF_00505}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00505}.
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DR   EMBL; CP000083; AAZ28374.1; -; Genomic_DNA.
DR   RefSeq; WP_011044649.1; NC_003910.7.
DR   AlphaFoldDB; Q47XA7; -.
DR   SMR; Q47XA7; -.
DR   STRING; 167879.CPS_3901; -.
DR   EnsemblBacteria; AAZ28374; AAZ28374; CPS_3901.
DR   KEGG; cps:CPS_3901; -.
DR   eggNOG; COG0326; Bacteria.
DR   HOGENOM; CLU_006684_3_0_6; -.
DR   OMA; MRRMKEM; -.
DR   OrthoDB; 246194at2; -.
DR   Proteomes; UP000000547; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.120.790; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   HAMAP; MF_00505; HSP90; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR019805; Heat_shock_protein_90_CS.
DR   InterPro; IPR037196; HSP90_C.
DR   InterPro; IPR001404; Hsp90_fam.
DR   InterPro; IPR020575; Hsp90_N.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR11528; PTHR11528; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00183; HSP90; 1.
DR   PIRSF; PIRSF002583; Hsp90; 1.
DR   PRINTS; PR00775; HEATSHOCK90.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF110942; SSF110942; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS00298; HSP90; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Reference proteome;
KW   Stress response.
FT   CHAIN           1..653
FT                   /note="Chaperone protein HtpG"
FT                   /id="PRO_0000224202"
FT   REGION          1..361
FT                   /note="A; substrate-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          362..578
FT                   /note="B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          579..653
FT                   /note="C"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
SQ   SEQUENCE   653 AA;  73392 MW;  30440B15A9A37D0D CRC64;
     MSETNQVQNH AFASDNAKIL QLMIHSLYSN KEIFLRELVS NAADAADKLR FKALSDNTLY
     ENDGDLRVRV SCDKENNTLT ISDNGIGMNV DEVIEHLGTI AKSGTAEFFS QLSGDQASDS
     QLIGQFGVGF YSAFIVADKV TVRTRKAGDS ATDGVEWISA GEGEFTTAKI EKTNRGTDII
     LHLKEDESEY ADDWRLKSIV TKYSDHISVS VEMLTAEVPA VEAVAEVTDE KDNVTRPAAD
     AVDAIPALWE PVNKATALWT REKADITDEE YKEFYKHVSH DFGDPLLWEH NRVEGKTEYT
     SLLYVPTKAP FDMYNREKQH GLKLFVQRVF IMDDAEQFMP TYLRFVKGLL DSNDLPLNVS
     REILQDNKVT QAIRKGCTKR VLKMLEKLGN KDADKYQGFW DEFGQVLKEG PAEDHANKEQ
     VAGLLRFAST HEDSTTQNVS LASYIERMKE GQDKIYFVVA DSFEAAKNSP HLEVFRKKGI
     EVLLMSDRID EWLVSHLTEF DGKQLQSVTR GGLDLGDMDD AETKEAQEKL EKEYDSVVKR
     IKASLDGKVK EVKLSQRLTD SPACIVADDD DMSSQMAKLM ASVGQEVPDT LPIFEINGEH
     ALVKHVADEQ DDDMFNQWVE VLFEQAMLAE RGSLKDPASF VSRLNKLMLS LTK