ID   HTPG_FRACC              Reviewed;         650 AA.
AC   Q2JGG1;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Chaperone protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=Heat shock protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=High temperature protein G {ECO:0000255|HAMAP-Rule:MF_00505};
GN   Name=htpG {ECO:0000255|HAMAP-Rule:MF_00505};
GN   OrderedLocusNames=Francci3_0243;
OS   Frankia casuarinae (strain DSM 45818 / CECT 9043 / CcI3).
OC   Bacteria; Actinobacteria; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=106370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45818 / CECT 9043 / CcI3;
RX   PubMed=17151343; DOI=10.1101/gr.5798407;
RA   Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA   Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA   Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA   Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA   Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA   Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA   Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA   Benson D.R.;
RT   "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT   reflect host range and host plant biogeography.";
RL   Genome Res. 17:7-15(2007).
CC   -!- FUNCTION: Molecular chaperone. Has ATPase activity. {ECO:0000255|HAMAP-
CC       Rule:MF_00505}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00505}.
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DR   EMBL; CP000249; ABD09631.1; -; Genomic_DNA.
DR   RefSeq; WP_011434711.1; NZ_JENI01000004.1.
DR   AlphaFoldDB; Q2JGG1; -.
DR   SMR; Q2JGG1; -.
DR   STRING; 106370.Francci3_0243; -.
DR   PRIDE; Q2JGG1; -.
DR   EnsemblBacteria; ABD09631; ABD09631; Francci3_0243.
DR   KEGG; fra:Francci3_0243; -.
DR   eggNOG; COG0326; Bacteria.
DR   HOGENOM; CLU_006684_3_0_11; -.
DR   OMA; MRRMKEM; -.
DR   OrthoDB; 246194at2; -.
DR   PhylomeDB; Q2JGG1; -.
DR   Proteomes; UP000001937; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.120.790; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   HAMAP; MF_00505; HSP90; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR019805; Heat_shock_protein_90_CS.
DR   InterPro; IPR037196; HSP90_C.
DR   InterPro; IPR001404; Hsp90_fam.
DR   InterPro; IPR020575; Hsp90_N.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR11528; PTHR11528; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00183; HSP90; 1.
DR   PIRSF; PIRSF002583; Hsp90; 1.
DR   PRINTS; PR00775; HEATSHOCK90.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF110942; SSF110942; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS00298; HSP90; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Reference proteome;
KW   Stress response.
FT   CHAIN           1..650
FT                   /note="Chaperone protein HtpG"
FT                   /id="PRO_0000236994"
FT   REGION          1..356
FT                   /note="A; substrate-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          222..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          357..572
FT                   /note="B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          573..650
FT                   /note="C"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
SQ   SEQUENCE   650 AA;  72845 MW;  F9F4B59D70C20C08 CRC64;
     MSTRVETLEF QAEARQLLQL MVHSIYSNKD IFLRELISNA SDALDKLRIA SLVKDGPRVD
     SADLRIEIEA DVNARTLTVR DNGIGMSRDE VVGLIGTIAK SGTAELLRKL RESEDGAASS
     DLIGQFGVGF YSTFMVADKV TLLTGKAGES GGTRWESDGA GTYVIETVDD APRGTAVTVH
     LKPEDSEDRL YDYTDENKIR EIVKRYSDFI AWPIRLVSAP AAKDRDSNDD GTAESGAGAE
     NAGDRPLNSM KALWARPQSE VDKAEYDQFY QHLSHDWTGP LEVIHMKGEG TFEYEALLFI
     PSRAPLDLFT RDARRGVQLY VKRVFIMDDC AELLPNYLRF VRGVVDTHDL SLNISREILQ
     QDRRIQLVRR RLVKKILASI RALQENDAER YRTLWKEFGA ALKEGLLEDA DNQDAILGLV
     SVDSTHDADR PTTLREYIER MKDAQNEIYY LTGDSRGMIE NSPHMEAFRA KGYEVLILTD
     PVDEVWVERV AEFDGKPLKS IAKGEVDLDT DDEKKSSEAE REQLRKDFAA LLPWLAAKLE
     DDVKEVRLSS RLTTSPACLV GDTFDMTPAL EKMYRAMGHE MPRPKRILEL NPTHALVMGL
     RAAHERDADS AALGDTAELL YGMALLAEGG ELRDPARFTR LLAERLAEAL