ID   HTPG_NITHX              Reviewed;         638 AA.
AC   Q1QHD7;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Chaperone protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=Heat shock protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=High temperature protein G {ECO:0000255|HAMAP-Rule:MF_00505};
GN   Name=htpG {ECO:0000255|HAMAP-Rule:MF_00505}; OrderedLocusNames=Nham_3632;
OS   Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Nitrobacter.
OX   NCBI_TaxID=323097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10229 / NCIMB 13809 / X14;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L.,
RA   O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T.,
RA   Gentry M.E., Bruce D., Richardson P.;
RT   "Complete sequence of chromosome of Nitrobacter hamburgensis X14.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Molecular chaperone. Has ATPase activity. {ECO:0000255|HAMAP-
CC       Rule:MF_00505}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00505}.
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DR   EMBL; CP000319; ABE64360.1; -; Genomic_DNA.
DR   RefSeq; WP_011512001.1; NC_007964.1.
DR   AlphaFoldDB; Q1QHD7; -.
DR   SMR; Q1QHD7; -.
DR   STRING; 323097.Nham_3632; -.
DR   EnsemblBacteria; ABE64360; ABE64360; Nham_3632.
DR   KEGG; nha:Nham_3632; -.
DR   eggNOG; COG0326; Bacteria.
DR   HOGENOM; CLU_006684_3_0_5; -.
DR   OMA; MRRMKEM; -.
DR   OrthoDB; 246194at2; -.
DR   Proteomes; UP000001953; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.120.790; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   HAMAP; MF_00505; HSP90; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR019805; Heat_shock_protein_90_CS.
DR   InterPro; IPR037196; HSP90_C.
DR   InterPro; IPR001404; Hsp90_fam.
DR   InterPro; IPR020575; Hsp90_N.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR11528; PTHR11528; 1.
DR   Pfam; PF00183; HSP90; 1.
DR   PIRSF; PIRSF002583; Hsp90; 1.
DR   PRINTS; PR00775; HEATSHOCK90.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF110942; SSF110942; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS00298; HSP90; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Reference proteome;
KW   Stress response.
FT   CHAIN           1..638
FT                   /note="Chaperone protein HtpG"
FT                   /id="PRO_0000258516"
FT   REGION          1..343
FT                   /note="A; substrate-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          344..557
FT                   /note="B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          558..638
FT                   /note="C"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
SQ   SEQUENCE   638 AA;  69605 MW;  A073C02C60682C9A CRC64;
     MTSTIDSDGA AESRVFEADV AKLLQMMVHS VYSDKDVFLR ELISNAADAC ERLRYDAISD
     PALLADDARP QIAITIDAER RQLTVDDNGI GMSRDEMVDA LGTIARSGTK AFIEQAKVEQ
     AKSAEAGDGV TVIGQFGVGF YSAFMVADQV DVISRRAGAG EAWRWSSDGK GTFTVTPADE
     SEAPARGTRV MLHLTEDAKG YTDRLKLEQI VREQSGHVPV PIVLVEQPGA APTEIADGAA
     LWTKPRGEIG TSEYVDFYRS VAGHFDEPAL TVHFRAEGRQ EFTALLFVPQ TRSFDLFETD
     RKGPIKLYVK RVFITDDADL LPRYLRFVRG VVDSADLPLN ISREMIQESP ILAAIKKSIT
     GRVLSELEKL AEKDAQAYGK VWEAFGPMFK EGIYDAADRR DAILSLCRFR TTAGSLRSLK
     DYVGALKDNQ TSIYYLAGQD AARLEASPHL EGFRARGVEV LLLSDPVDSF WVTSAPSFEG
     KPFKSVTQGD TDLAAIPRVD ASAETLQEVS ASVTEFLAFL KTTLADLVSD VRSSERLTDS
     PVCLIAAESG PDRQLEKILV GVGQLTGASK PVLEVNPRHP LIASLAALGD GDRAFKEDTA
     RMLLDDARVL DGDRPSDALE FSRRLARIVE RGLRGSTA