ID   HTPG_PSEU2              Reviewed;         635 AA.
AC   Q4ZUW2;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 2.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Chaperone protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=Heat shock protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=High temperature protein G {ECO:0000255|HAMAP-Rule:MF_00505};
GN   Name=htpG {ECO:0000255|HAMAP-Rule:MF_00505}; OrderedLocusNames=Psyr_2017;
OS   Pseudomonas syringae pv. syringae (strain B728a).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=205918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B728a;
RX   PubMed=16043691; DOI=10.1073/pnas.0504930102;
RA   Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A.,
RA   Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S.,
RA   Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M.,
RA   Kyrpides N.C., Ivanova N., Lindow S.E.;
RT   "Comparison of the complete genome sequences of Pseudomonas syringae pv.
RT   syringae B728a and pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005).
CC   -!- FUNCTION: Molecular chaperone. Has ATPase activity. {ECO:0000255|HAMAP-
CC       Rule:MF_00505}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAY37060.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000075; AAY37060.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_003406139.1; NC_007005.1.
DR   RefSeq; YP_235098.1; NC_007005.1.
DR   AlphaFoldDB; Q4ZUW2; -.
DR   SMR; Q4ZUW2; -.
DR   STRING; 205918.Psyr_2017; -.
DR   EnsemblBacteria; AAY37060; AAY37060; Psyr_2017.
DR   KEGG; psb:Psyr_2017; -.
DR   PATRIC; fig|205918.7.peg.2060; -.
DR   eggNOG; COG0326; Bacteria.
DR   HOGENOM; CLU_006684_3_0_6; -.
DR   Proteomes; UP000000426; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.120.790; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   HAMAP; MF_00505; HSP90; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR019805; Heat_shock_protein_90_CS.
DR   InterPro; IPR037196; HSP90_C.
DR   InterPro; IPR001404; Hsp90_fam.
DR   InterPro; IPR020575; Hsp90_N.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR11528; PTHR11528; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00183; HSP90; 1.
DR   PIRSF; PIRSF002583; Hsp90; 1.
DR   PRINTS; PR00775; HEATSHOCK90.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF110942; SSF110942; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS00298; HSP90; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Stress response.
FT   CHAIN           1..635
FT                   /note="Chaperone protein HtpG"
FT                   /id="PRO_0000224224"
FT   REGION          1..343
FT                   /note="A; substrate-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          344..560
FT                   /note="B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          561..635
FT                   /note="C"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
SQ   SEQUENCE   635 AA;  71332 MW;  C9292450E9094E39 CRC64;
     MSVETQKETL GFQTEVKQLL HLMIHSLYSN KEIFLRELIS NASDAVDKLR FEALSKPELL
     EGGAELKIRV SFDKDAKTVT LEDNGIGMSR EDVITHLGTI AKSGTADFMK NLSGDQKKDS
     HLIGQFGVGF YSAFIVADQV EVFSRRAGTP ASEGVHWSSK GEGEFEVATV DKADRGTRIV
     LHLKNGEEEF ADGYRLRNII KKYSDHIALP IELPKEQAPA AEGEEPAALE WETVNRASAL
     WTRPRTEVKD EEYQEFYKHV AHDYENPLSW SHNKVEGKLE YTSLLYVPAR APFDLYQREA
     PRGLKLYVQR VFVMDQAESF LPLYMRFVKG VVDSNDLSLN VSREILQKDP IIDSMKSALT
     KRVLDMLEKL AKNEPEKYKG FWKNFGQVLK EGPAEDFANK EKIAGLLRFA STSDDSGEQS
     VSLAEYLARA KEGQDKIYYL TGESYAQVKN SPHLEVFRKK GIEVLLLTDR IDEWLMSYLS
     DFDGKGFVDV ARGDLDLGNL DSEEDKKAQE EIAKDKEGLI ERLKAALGES VSEVRVSHRL
     TDSPAILAIG EQDMGLQMRQ ILEASGQKVP DSKPIFEFNP AHPLIGKLDA EQSEDRFGDL
     SHILFDQAAL AAGDSLKDPA AYVRRLNKLL VELSV