ID   HTPG_RHOPA              Reviewed;         628 AA.
AC   P61187;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2004, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Chaperone protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=Heat shock protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=High temperature protein G {ECO:0000255|HAMAP-Rule:MF_00505};
GN   Name=htpG {ECO:0000255|HAMAP-Rule:MF_00505}; OrderedLocusNames=RPA4815;
OS   Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=258594;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-98 / CGA009;
RX   PubMed=14704707; DOI=10.1038/nbt923;
RA   Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L.,
RA   Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R.,
RA   Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C.,
RA   Harrison F.H., Gibson J., Harwood C.S.;
RT   "Complete genome sequence of the metabolically versatile photosynthetic
RT   bacterium Rhodopseudomonas palustris.";
RL   Nat. Biotechnol. 22:55-61(2004).
CC   -!- FUNCTION: Molecular chaperone. Has ATPase activity. {ECO:0000255|HAMAP-
CC       Rule:MF_00505}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00505}.
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DR   EMBL; BX572608; CAE30255.1; -; Genomic_DNA.
DR   RefSeq; WP_011160347.1; NC_005296.1.
DR   AlphaFoldDB; P61187; -.
DR   SMR; P61187; -.
DR   STRING; 258594.RPA4815; -.
DR   PRIDE; P61187; -.
DR   EnsemblBacteria; CAE30255; CAE30255; RPA4815.
DR   GeneID; 66895977; -.
DR   KEGG; rpa:RPA4815; -.
DR   eggNOG; COG0326; Bacteria.
DR   HOGENOM; CLU_006684_3_0_5; -.
DR   OMA; MRRMKEM; -.
DR   PhylomeDB; P61187; -.
DR   BioCyc; RPAL258594:TX73_RS24625-MON; -.
DR   Proteomes; UP000001426; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.120.790; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   HAMAP; MF_00505; HSP90; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR037196; HSP90_C.
DR   InterPro; IPR001404; Hsp90_fam.
DR   InterPro; IPR020575; Hsp90_N.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR11528; PTHR11528; 1.
DR   Pfam; PF00183; HSP90; 1.
DR   PIRSF; PIRSF002583; Hsp90; 1.
DR   PRINTS; PR00775; HEATSHOCK90.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF110942; SSF110942; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Reference proteome;
KW   Stress response.
FT   CHAIN           1..628
FT                   /note="Chaperone protein HtpG"
FT                   /id="PRO_0000063009"
FT   REGION          1..334
FT                   /note="A; substrate-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          335..550
FT                   /note="B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          551..628
FT                   /note="C"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
SQ   SEQUENCE   628 AA;  69468 MW;  39B93DDBD1AA6A1B CRC64;
     MTMTDTASET KPFQAEVAEL LNLMVHSVYS ETDIFLRELI SNASDALDKL RYESIAKPEL
     MEKGGEPKIR IIPKKAPDTL TIVDNGIGMD RQELIDNLGT IAKSGTKSFI SKLAETKDSA
     GLIGQFGVGF YAAFMVADKI TVTSRRAGSD DVWTWTSAGG AGFEIAPASE EAAARVERGT
     EIVLHLKPDA SKYLEDWQIE RIVTEYSDNI QFPILLMPEE GEPRQINSAS ALWQRSKSEL
     SEDDYKQAYK QIAGAFDDPA MTLHYRAEGR QSYAVLLFAP STKPFDLFEP ERKGKIKLYV
     RRVFITSEAE LLPPYLRFLR GVIDSEDLPL NLSREMLQKN PQLAQIRTAV TGKVISELES
     LADKKPEDFT KIWDAFGPVL KEGLYEDFER REKLLSLARF TTTAGEKRSL KQYVEAMKEN
     QTEIYYLVGD SLERLKSNPK LESATARGIE VLLLTDPVDA FWTSGQLDFG GKPLKSLSQG
     DVNFDLIPKL EQDQDKDNKD EAKVDEATVI AVIKDALGER VSDVKASQRL TSSASCLVAG
     GMGPDRELEK LLARANKGAG SKPILEINLQ HPLVAALGDT KTDKAEAADL AFLLLEQAQI
     LDGELPEDPA AFASRLNRLV LRGVVAHG