ID   HTPG_VIBA3              Reviewed;         634 AA.
AC   B7VII6;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Chaperone protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=Heat shock protein HtpG {ECO:0000255|HAMAP-Rule:MF_00505};
DE   AltName: Full=High temperature protein G {ECO:0000255|HAMAP-Rule:MF_00505};
GN   Name=htpG {ECO:0000255|HAMAP-Rule:MF_00505}; OrderedLocusNames=VS_2269;
OS   Vibrio atlanticus (strain LGP32) (Vibrio splendidus (strain Mel32)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=575788;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LGP32;
RA   Mazel D., Le Roux F.;
RT   "Vibrio splendidus str. LGP32 complete genome.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Molecular chaperone. Has ATPase activity. {ECO:0000255|HAMAP-
CC       Rule:MF_00505}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00505}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00505}.
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DR   EMBL; FM954972; CAV19432.1; -; Genomic_DNA.
DR   RefSeq; WP_012604546.1; NC_011753.2.
DR   AlphaFoldDB; B7VII6; -.
DR   SMR; B7VII6; -.
DR   STRING; 575788.VS_2269; -.
DR   PRIDE; B7VII6; -.
DR   EnsemblBacteria; CAV19432; CAV19432; VS_2269.
DR   KEGG; vsp:VS_2269; -.
DR   PATRIC; fig|575788.5.peg.3531; -.
DR   eggNOG; COG0326; Bacteria.
DR   HOGENOM; CLU_006684_3_0_6; -.
DR   OMA; MRRMKEM; -.
DR   OrthoDB; 246194at2; -.
DR   Proteomes; UP000009100; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.120.790; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   HAMAP; MF_00505; HSP90; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR019805; Heat_shock_protein_90_CS.
DR   InterPro; IPR037196; HSP90_C.
DR   InterPro; IPR001404; Hsp90_fam.
DR   InterPro; IPR020575; Hsp90_N.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR11528; PTHR11528; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00183; HSP90; 1.
DR   PIRSF; PIRSF002583; Hsp90; 1.
DR   PRINTS; PR00775; HEATSHOCK90.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF110942; SSF110942; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS00298; HSP90; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Reference proteome;
KW   Stress response.
FT   CHAIN           1..634
FT                   /note="Chaperone protein HtpG"
FT                   /id="PRO_1000146010"
FT   REGION          1..344
FT                   /note="A; substrate-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          345..561
FT                   /note="B"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
FT   REGION          562..634
FT                   /note="C"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00505"
SQ   SEQUENCE   634 AA;  71915 MW;  186D203936378FA7 CRC64;
     MSETATQNKE TRGFQSEVKQ LLHLMIHSLY SNKEIFLREL ISNASDAADK LRFQALSNGD
     LYQGDADLGV KLSFNAEANT LTISDNGIGM SRDNVIEHLG TIAKSGTADF FSKLSEDQSK
     DSQLIGQFGV GFYSAFIVAD AVTVRTRAAG LANDQAVQWH SAGEGDYTIE DITKESRGTD
     IILHMREDGK EFLNEWRLRE VIGKYSDHIG IPVSIFTAVK DDEGKDTEEK HWEQINKAQA
     LWTRNKSDIE KEEYQEFYKH VSHDFADPLT WSHNKVEGKN DYTSLLYIPA KAPWDMMNRD
     HKSGLKLYVQ RVFIMDDAEQ FMPSYMRFVR GLIDSNDLPL NVSREILQDN KVTQSLRGAC
     TKRVLTMLER MAKNDNDKYL EFWKEFGLVL KEGPAEDMAN KEKIAGLLRF SSTEVDSSEQ
     TIGLASYVER MKEGQDKIYY LTADSYAAAK NSPHLEQFKA KGIEVVLMYD RIDEYVMNYL
     TDFDGKQFQS ITKAGLDLSK FEGEEEKEKQ KETEEEFKSV VERTQSYLGG RVKEVRTTFK
     LATTPAVVVT DDFEMGTQMA KLLEAAGQAA PEVKYIFEIN PEHALVKQMA DEADEQAFGR
     WVELLLGQAM LAEKGSMEDP SQFLGAINEL LTKR