ID   HTRL_ECOLI              Reviewed;         285 AA.
AC   P25666; Q2M7T2;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 2.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Protein HtrL;
GN   Name=htrL {ECO:0000312|EMBL:AAA91059.1}; Synonyms=yibB;
GN   OrderedLocusNames=b3618, JW5644;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RA   Raina S., Missiakas D., Georgopoulos C.;
RT   "The Escherichia coli htrL gene, cloning, sequencing, and transcriptional
RT   regulation: evidence for its positive regulation by the rfaH gene
RT   product.";
RL   Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA   Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT   "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT   from 76.0 to 81.5 minutes.";
RL   Nucleic Acids Res. 22:2576-2586(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-214.
RC   STRAIN=K12;
RX   PubMed=2198271; DOI=10.1128/jb.172.8.4652-4660.1990;
RA   Pegues J.C., Chen L., Gordon A.W., Ding L., Coleman W.G. Jr.;
RT   "Cloning, expression, and characterization of the Escherichia coli K-12
RT   rfaD gene.";
RL   J. Bacteriol. 172:4652-4660(1990).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 213-285.
RC   STRAIN=K12;
RX   PubMed=3287333; DOI=10.1093/nar/16.8.3586;
RA   Aronson B.D., Ravnikar P.D., Somerville R.L.;
RT   "Nucleotide sequence of the 2-amino-3-ketobutyrate coenzyme A ligase (kbl)
RT   gene of E. coli.";
RL   Nucleic Acids Res. 16:3586-3586(1988).
RN   [7]
RP   INDUCTION.
RX   PubMed=10899145; DOI=10.1101/gr.10.7.959;
RA   Alimi J.P., Poirot O., Lopez F., Claverie J.M.;
RT   "Reverse transcriptase-polymerase chain reaction validation of 25 'orphan'
RT   genes from Escherichia coli K-12 MG1655.";
RL   Genome Res. 10:959-966(2000).
CC   -!- INDUCTION: Expressed in both exponential and stationary phases.
CC       {ECO:0000269|PubMed:10899145}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA91059.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAB18595.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M94888; AAA91059.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00039; AAB18595.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC76642.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77674.1; -; Genomic_DNA.
DR   EMBL; M33577; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; X06690; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; S47839; S47839.
DR   RefSeq; NP_418075.2; NC_000913.3.
DR   RefSeq; WP_000842820.1; NZ_LN832404.1.
DR   AlphaFoldDB; P25666; -.
DR   BioGRID; 4263300; 313.
DR   STRING; 511145.b3618; -.
DR   jPOST; P25666; -.
DR   PaxDb; P25666; -.
DR   PRIDE; P25666; -.
DR   EnsemblBacteria; AAC76642; AAC76642; b3618.
DR   EnsemblBacteria; BAE77674; BAE77674; BAE77674.
DR   GeneID; 948137; -.
DR   KEGG; ecj:JW5644; -.
DR   KEGG; eco:b3618; -.
DR   PATRIC; fig|511145.12.peg.3738; -.
DR   EchoBASE; EB1174; -.
DR   eggNOG; ENOG502ZACE; Bacteria.
DR   HOGENOM; CLU_084735_0_0_6; -.
DR   InParanoid; P25666; -.
DR   OMA; PTHIITI; -.
DR   PhylomeDB; P25666; -.
DR   BioCyc; EcoCyc:EG11188-MON; -.
DR   PRO; PR:P25666; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   InterPro; IPR011735; HtrL.
DR   Pfam; PF09612; HtrL_YibB; 1.
DR   TIGRFAMs; TIGR02192; HtrL_YibB; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..285
FT                   /note="Protein HtrL"
FT                   /id="PRO_0000084087"
SQ   SEQUENCE   285 AA;  33458 MW;  5EF61BE2D95A601D CRC64;
     MKSSTTIITA YFDIGRGDWT ANKGFREKLA RSVDVYFSYF ERLAALENEM IIFTSPDLKP
     RVEAIRNGKP TTVIVIDIKK KFRYIRSRIE KIQKDESFTN RLEPRQLKNP EYWSPEYVLV
     CNLKAYFVNK AINMGLVKTP LVAWIDFGYC HKPNVTRGLK IWDFPFDESK MHLFTIKKGL
     TVTSQQQVFD FMIGNHVYII GGAIVGSQHK WKEFYKLVLE SQKITLNNNI VDDDQGIFVM
     CYYKRPDLFN LNYLGRGKWF DLFRCFRSNT LGAKMQALRI FLSRK