HUA2_YEAST
ID HUA2_YEAST Reviewed; 243 AA.
AC Q12134; D6W2Y2;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Protein HUA2;
GN Name=HUA2; OrderedLocusNames=YOR284W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8896271;
RX DOI=10.1002/(sici)1097-0061(199609)12:10b%3c1059::aid-yea994%3e3.0.co;2-7;
RA Cheret G., Bernardi A., Sor F.J.;
RT "DNA sequence analysis of the VPH1-SNF2 region on chromosome XV of
RT Saccharomyces cerevisiae.";
RL Yeast 12:1059-1064(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169874;
RA Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL Nature 387:98-102(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [6]
RP FUNCTION.
RX PubMed=14566057; DOI=10.1073/pnas.2132527100;
RA Samanta M.P., Liang S.;
RT "Predicting protein functions from redundancies in large-scale protein
RT interaction networks.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:12579-12583(2003).
CC -!- FUNCTION: May have a role in actin patch assembly.
CC {ECO:0000269|PubMed:14566057}.
CC -!- INTERACTION:
CC Q12134; P15891: ABP1; NbExp=4; IntAct=EBI-37262, EBI-2036;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 1360 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; X89633; CAA61788.1; -; Genomic_DNA.
DR EMBL; Z75192; CAA99511.1; -; Genomic_DNA.
DR EMBL; BK006948; DAA11048.1; -; Genomic_DNA.
DR PIR; S67186; S67186.
DR RefSeq; NP_014927.3; NM_001183703.3.
DR AlphaFoldDB; Q12134; -.
DR BioGRID; 34671; 58.
DR DIP; DIP-1472N; -.
DR IntAct; Q12134; 24.
DR MINT; Q12134; -.
DR STRING; 4932.YOR284W; -.
DR iPTMnet; Q12134; -.
DR MaxQB; Q12134; -.
DR PaxDb; Q12134; -.
DR PRIDE; Q12134; -.
DR EnsemblFungi; YOR284W_mRNA; YOR284W; YOR284W.
DR GeneID; 854458; -.
DR KEGG; sce:YOR284W; -.
DR SGD; S000005810; HUA2.
DR VEuPathDB; FungiDB:YOR284W; -.
DR HOGENOM; CLU_1143319_0_0_1; -.
DR OMA; CKRSTHQ; -.
DR BioCyc; YEAST:G3O-33770-MON; -.
DR PRO; PR:Q12134; -.
DR Proteomes; UP000002311; Chromosome XV.
DR RNAct; Q12134; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
PE 1: Evidence at protein level;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..243
FT /note="Protein HUA2"
FT /id="PRO_0000270558"
SQ SEQUENCE 243 AA; 28414 MW; B1F3A81B7C0F65AC CRC64;
MQQTKFGKMY LDHDSVVEYS EDEIVEADRI TLGYKKRLSM IENQMRHLLE DFSLDVQQIE
PILADLQKYY DAFLQLLQKR NKSLQCKRST HQPVPSPMNS QTSTNAKVNL SGKLMKFQLN
SVQKFDEENI LRILQNKIEF EHYFQIDKGK KQKVLLLAVY QCLNGPTRLH KVLNIEGIIH
NNSIRTILGK QVSSSKWTVF LYDVKLVLLA HRQDVPNLET SKMIVRYGDL FPCALYFKDH
TAY
