HUNB_DROAD
ID HUNB_DROAD Reviewed; 192 AA.
AC O46232; O46233;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 2.
DT 25-MAY-2022, entry version 53.
DE RecName: Full=Protein hunchback;
DE Flags: Fragments;
GN Name=hb;
OS Drosophila adiastola (Fruit fly) (Idiomyia adiastola).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Hawaiian Drosophila.
OX NCBI_TaxID=7261;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11975337; DOI=10.1093/sysbio/46.4.654;
RA Baker R.H., DeSalle R.;
RT "Multiple sources of character information and the phylogeny of Hawaiian
RT Drosophilids.";
RL Syst. Biol. 46:654-673(1997).
CC -!- FUNCTION: Gap class segmentation protein that controls development of
CC head structures. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the hunchback C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; U92996; AAC03244.1; -; Genomic_DNA.
DR EMBL; U92997; AAC03245.1; -; Genomic_DNA.
DR AlphaFoldDB; O46232; -.
DR SMR; O46232; -.
DR FlyBase; FBgn0024138; Dadi\hb.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0035282; P:segmentation; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Developmental protein; DNA-binding; Gap protein; Metal-binding; Nucleus;
KW Repeat; Zinc; Zinc-finger.
FT CHAIN <1..>192
FT /note="Protein hunchback"
FT /id="PRO_0000046950"
FT REGION 16..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 151..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..30
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_CONS 101..102
FT /evidence="ECO:0000305"
FT NON_TER 1
FT NON_TER 192
SQ SEQUENCE 192 AA; 21174 MW; D4499A5787C8FCDC CRC64;
WYSSMFAANI KQEPISHHHH HHHAHHSRRQ HPHDSNSNSN ASSPHQSPLP SPNPPSNTNL
QLEQYLKHQQ QQQQQQHQQQ PMDTLCAAAM TPSPSNNDQN SPLTWPGLPN PMQSIMPANL
RPSPNTTTTT PPAAAPAAAT IALQANDKLQ ALTPPMDVTP PKSPAKSQQS CAEPEKEHDL
MSNSSEDMKY MA