HUNB_DRODA
ID HUNB_DRODA Reviewed; 195 AA.
AC O46262; O46263;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 2.
DT 25-MAY-2022, entry version 53.
DE RecName: Full=Protein hunchback;
DE Flags: Fragments;
GN Name=hb;
OS Drosophila dasycnemia (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Hawaiian Drosophila; split tarsi subgroup.
OX NCBI_TaxID=58308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11975337; DOI=10.1093/sysbio/46.4.654;
RA Baker R.H., DeSalle R.;
RT "Multiple sources of character information and the phylogeny of Hawaiian
RT Drosophilids.";
RL Syst. Biol. 46:654-673(1997).
CC -!- FUNCTION: Gap class segmentation protein that controls development of
CC head structures. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the hunchback C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U93026; AAC03274.1; -; Genomic_DNA.
DR EMBL; U93027; AAC03275.1; -; Genomic_DNA.
DR AlphaFoldDB; O46262; -.
DR FlyBase; FBgn0024069; Ddas\hb.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0035282; P:segmentation; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Developmental protein; DNA-binding; Gap protein; Metal-binding; Nucleus;
KW Repeat; Zinc; Zinc-finger.
FT CHAIN <1..>195
FT /note="Protein hunchback"
FT /id="PRO_0000046953"
FT REGION 16..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 64..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_CONS 102..103
FT /evidence="ECO:0000305"
FT NON_TER 1
FT NON_TER 195
SQ SEQUENCE 195 AA; 21335 MW; 4DA02122E1532AC3 CRC64;
WYSSMFAANI KQEPISHHHH HHHAHHSHHA HDSNSNSNAS SPHQSPLPSP NPPSHTNLQL
EQYLKQQQQQ QQQHQHQQQQ QPMDTLCAAA MTPSPSNNDQ NSLGWLVGLP NPMQTIMPAN
MRPSPTATTA TAAAAAPTTT AAAIALQAND KLQALTPPMD VTPPKSPAKS QQSCAEPEKE
HDLMSNSSED MKYMA