ID   HUNB_DROSO              Reviewed;         159 AA.
AC   O46258; O46259;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 2.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Protein hunchback;
DE   Flags: Fragments;
GN   Name=hb;
OS   Drosophila soonae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Hawaiian Drosophila;
OC   modified mouthparts group incertae sedis.
OX   NCBI_TaxID=58310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11975337; DOI=10.1093/sysbio/46.4.654;
RA   Baker R.H., DeSalle R.;
RT   "Multiple sources of character information and the phylogeny of Hawaiian
RT   Drosophilids.";
RL   Syst. Biol. 46:654-673(1997).
CC   -!- FUNCTION: Gap class segmentation protein that controls development of
CC       head structures. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the hunchback C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; U93022; AAC03270.1; -; Genomic_DNA.
DR   EMBL; U93023; AAC03271.1; -; Genomic_DNA.
DR   AlphaFoldDB; O46258; -.
DR   FlyBase; FBgn0023615; Dsoo\hb.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035282; P:segmentation; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Developmental protein; DNA-binding; Gap protein; Metal-binding; Nucleus;
KW   Repeat; Zinc; Zinc-finger.
FT   CHAIN           <1..>159
FT                   /note="Protein hunchback"
FT                   /id="PRO_0000046963"
FT   REGION          18..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          119..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..33
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_CONS        64..65
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
FT   NON_TER         159
SQ   SEQUENCE   159 AA;  17757 MW;  1EE7BC99DAB89916 CRC64;
     WYSSMFAANI KQEPISHHNH HHHHHHGHHQ HQQRHNSNSN ASSPHQSPLP NLQLEQYLKQ
     QQQQPLMWSG LPNPMQTIMP ANMRPSPTAA TAATTTELCA PTTTVAAIAM QANDKLQALT
     PPMDVTPPKS PAKSQQSCAE PEKEHDLMSN SSEDMKYMA