ID   HUPD_AZOCH              Reviewed;         379 AA.
AC   P42033;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Hydrogenase expression/formation protein HupD;
GN   Name=hupD;
OS   Azotobacter chroococcum mcd 1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Azotobacter.
OX   NCBI_TaxID=355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1526470; DOI=10.1016/0378-1097(92)90462-w;
RA   Du L., Stejskal F., Tibelius K.H.;
RT   "Characterization of two genes (hupD and hupE) required for hydrogenase
RT   activity in Azotobacter chroococcum.";
RL   FEMS Microbiol. Lett. 75:93-101(1992).
CC   -!- SIMILARITY: Belongs to the HypD family. {ECO:0000305}.
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DR   EMBL; M92282; AAA22136.1; -; Genomic_DNA.
DR   PIR; I39743; I39743.
DR   AlphaFoldDB; P42033; -.
DR   SMR; P42033; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.11740; -; 2.
DR   Gene3D; 6.10.20.100; -; 1.
DR   InterPro; IPR002780; Hyd_form_HypD.
DR   InterPro; IPR042243; HypD_1.
DR   InterPro; IPR042244; HypD_2_sf.
DR   PANTHER; PTHR30149; PTHR30149; 1.
DR   Pfam; PF01924; HypD; 1.
DR   PIRSF; PIRSF005622; Hydrgn_mat_hypD; 1.
DR   TIGRFAMs; TIGR00075; hypD; 1.
PE   3: Inferred from homology;
KW   Iron; Metal-binding.
FT   CHAIN           1..379
FT                   /note="Hydrogenase expression/formation protein HupD"
FT                   /id="PRO_0000201447"
FT   BINDING         36
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250|UniProtKB:P24192"
FT   BINDING         64
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250|UniProtKB:P24192"
FT   BINDING         67
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250|UniProtKB:P24192"
SQ   SEQUENCE   379 AA;  41339 MW;  B93D6FF0C56E7A5B CRC64;
     MKYVDEFRDG ATARQLAARI AAEADPARQY RLMEFCGGHT HAIFRYGIPD LLPASVRLIH
     GPGCPVCVMP IGRLDMAIEL ARRPEVILCT YGDMLRVPAS GRVSLLKARA ESAAVRMLYS
     PAEALKLAQD NPSKEVVFFA IGFETTTPPT ALVIEQAQRL GLKNFSVFCN HVLTPAAMHA
     ILATPEARAG TLQLDGFIGP AHVSTVIGSA PYAPFPQQYG TPLVIAGFEP LDLLQALLML
     VRQLNEGRAE VENQFTRAVT AEGNRKAKAL TERVFEVRES FEWRGLGAVP HSALQIREAF
     AEFNAERRFA LEPRTGLENK ACECPAILRG AKSPRDCKLF GNPCTPDNPL GSCMVSSEGA
     CAAWYAYGRQ RQAAVEVAR