HUTP_BACC0
ID HUTP_BACC0 Reviewed; 146 AA.
AC B7JI81;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 25-MAY-2022, entry version 57.
DE RecName: Full=Hut operon positive regulatory protein {ECO:0000255|HAMAP-Rule:MF_00779};
GN Name=hutP {ECO:0000255|HAMAP-Rule:MF_00779};
GN OrderedLocusNames=BCAH820_3663;
OS Bacillus cereus (strain AH820).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=405535;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AH820;
RA Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A.,
RA Ravel J., Sutton G.;
RT "Genome sequence of Bacillus cereus AH820.";
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Antiterminator that binds to cis-acting regulatory sequences
CC on the mRNA in the presence of histidine, thereby suppressing
CC transcription termination and activating the hut operon for histidine
CC utilization. {ECO:0000255|HAMAP-Rule:MF_00779}.
CC -!- SUBUNIT: Homohexamer. {ECO:0000255|HAMAP-Rule:MF_00779}.
CC -!- SIMILARITY: Belongs to the HutP family. {ECO:0000255|HAMAP-
CC Rule:MF_00779}.
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DR EMBL; CP001283; ACK88789.1; -; Genomic_DNA.
DR RefSeq; WP_000926522.1; NC_011773.1.
DR AlphaFoldDB; B7JI81; -.
DR SMR; B7JI81; -.
DR EnsemblBacteria; ACK88789; ACK88789; BCAH820_3663.
DR KEGG; bcu:BCAH820_3663; -.
DR HOGENOM; CLU_148478_0_0_9; -.
DR OMA; REMHALY; -.
DR Proteomes; UP000001363; Chromosome.
DR GO; GO:0003729; F:mRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006547; P:histidine metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1510.10; -; 1.
DR HAMAP; MF_00779; HutP; 1.
DR InterPro; IPR015111; Regulatory_HutP.
DR InterPro; IPR023552; Regulatory_HutP_bacillales.
DR InterPro; IPR036482; Regulatory_HutP_sf.
DR Pfam; PF09021; HutP; 1.
DR SUPFAM; SSF111064; SSF111064; 1.
PE 3: Inferred from homology;
KW Activator; Histidine metabolism; RNA-binding; Transcription;
KW Transcription regulation.
FT CHAIN 1..146
FT /note="Hut operon positive regulatory protein"
FT /id="PRO_1000148459"
SQ SEQUENCE 146 AA; 15821 MW; EB176479A3BEAA09 CRC64;
MLLQGTHRIG RMAMLLALAD QNESPVLSIP KGWKYCTGKV GSMNSQKVVA AMETAAKSNQ
VIETDVYRET HALYHAIMEA LYGVTRGQIQ LADVLRTVGL RFAIVRGTPY DGKKEGEWVA
VALYGTIGAP VKGSEHEAIG LGINHI