ID   HUTP_BACC1              Reviewed;         146 AA.
AC   Q733H7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Hut operon positive regulatory protein {ECO:0000255|HAMAP-Rule:MF_00779};
GN   Name=hutP {ECO:0000255|HAMAP-Rule:MF_00779}; OrderedLocusNames=BCE_3681;
OS   Bacillus cereus (strain ATCC 10987 / NRS 248).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=222523;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10987 / NRS 248;
RX   PubMed=14960714; DOI=10.1093/nar/gkh258;
RA   Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L.,
RA   Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F.,
RA   Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D.;
RT   "The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic
RT   adaptations and a large plasmid related to Bacillus anthracis pXO1.";
RL   Nucleic Acids Res. 32:977-988(2004).
CC   -!- FUNCTION: Antiterminator that binds to cis-acting regulatory sequences
CC       on the mRNA in the presence of histidine, thereby suppressing
CC       transcription termination and activating the hut operon for histidine
CC       utilization. {ECO:0000255|HAMAP-Rule:MF_00779}.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000255|HAMAP-Rule:MF_00779}.
CC   -!- SIMILARITY: Belongs to the HutP family. {ECO:0000255|HAMAP-
CC       Rule:MF_00779}.
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DR   EMBL; AE017194; AAS42586.1; -; Genomic_DNA.
DR   RefSeq; WP_000926516.1; NC_003909.8.
DR   AlphaFoldDB; Q733H7; -.
DR   SMR; Q733H7; -.
DR   EnsemblBacteria; AAS42586; AAS42586; BCE_3681.
DR   GeneID; 59155847; -.
DR   GeneID; 64202201; -.
DR   GeneID; 67508301; -.
DR   KEGG; bca:BCE_3681; -.
DR   HOGENOM; CLU_148478_0_0_9; -.
DR   OMA; REMHALY; -.
DR   Proteomes; UP000002527; Chromosome.
DR   GO; GO:0003729; F:mRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006547; P:histidine metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1510.10; -; 1.
DR   HAMAP; MF_00779; HutP; 1.
DR   InterPro; IPR015111; Regulatory_HutP.
DR   InterPro; IPR023552; Regulatory_HutP_bacillales.
DR   InterPro; IPR036482; Regulatory_HutP_sf.
DR   Pfam; PF09021; HutP; 1.
DR   SUPFAM; SSF111064; SSF111064; 1.
PE   3: Inferred from homology;
KW   Activator; Histidine metabolism; RNA-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..146
FT                   /note="Hut operon positive regulatory protein"
FT                   /id="PRO_1000046821"
SQ   SEQUENCE   146 AA;  15822 MW;  EB17646463B76A1D CRC64;
     MLLQGTHRIG RMAMLLALAD ENESPVLSIP KGWKYCTGKV GSMNSQKVVA AMETAAKSNQ
     VIETDVYRET HALYHAIMEA LYGVTRGQIQ LADVLRTVGL RFAIVRGTPY DGKKEGEWVA
     VALYGTIGAP VKGSEHEAIG LGINHI