ID   HUTP_BACC4              Reviewed;         146 AA.
AC   B7HCD1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Hut operon positive regulatory protein {ECO:0000255|HAMAP-Rule:MF_00779};
GN   Name=hutP {ECO:0000255|HAMAP-Rule:MF_00779};
GN   OrderedLocusNames=BCB4264_A3761;
OS   Bacillus cereus (strain B4264).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=405532;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B4264;
RA   Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A.,
RA   Ravel J., Sutton G.;
RT   "Genome sequence of Bacillus cereus B4264.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Antiterminator that binds to cis-acting regulatory sequences
CC       on the mRNA in the presence of histidine, thereby suppressing
CC       transcription termination and activating the hut operon for histidine
CC       utilization. {ECO:0000255|HAMAP-Rule:MF_00779}.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000255|HAMAP-Rule:MF_00779}.
CC   -!- SIMILARITY: Belongs to the HutP family. {ECO:0000255|HAMAP-
CC       Rule:MF_00779}.
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DR   EMBL; CP001176; ACK61935.1; -; Genomic_DNA.
DR   RefSeq; WP_000926516.1; NZ_VEHB01000002.1.
DR   AlphaFoldDB; B7HCD1; -.
DR   SMR; B7HCD1; -.
DR   EnsemblBacteria; ACK61935; ACK61935; BCB4264_A3761.
DR   GeneID; 59155847; -.
DR   GeneID; 64202201; -.
DR   GeneID; 67508301; -.
DR   KEGG; bcb:BCB4264_A3761; -.
DR   HOGENOM; CLU_148478_0_0_9; -.
DR   OMA; REMHALY; -.
DR   Proteomes; UP000007096; Chromosome.
DR   GO; GO:0003729; F:mRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006547; P:histidine metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1510.10; -; 1.
DR   HAMAP; MF_00779; HutP; 1.
DR   InterPro; IPR015111; Regulatory_HutP.
DR   InterPro; IPR023552; Regulatory_HutP_bacillales.
DR   InterPro; IPR036482; Regulatory_HutP_sf.
DR   Pfam; PF09021; HutP; 1.
DR   SUPFAM; SSF111064; SSF111064; 1.
PE   3: Inferred from homology;
KW   Activator; Histidine metabolism; RNA-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..146
FT                   /note="Hut operon positive regulatory protein"
FT                   /id="PRO_1000133709"
SQ   SEQUENCE   146 AA;  15822 MW;  EB17646463B76A1D CRC64;
     MLLQGTHRIG RMAMLLALAD ENESPVLSIP KGWKYCTGKV GSMNSQKVVA AMETAAKSNQ
     VIETDVYRET HALYHAIMEA LYGVTRGQIQ LADVLRTVGL RFAIVRGTPY DGKKEGEWVA
     VALYGTIGAP VKGSEHEAIG LGINHI