HUTP_BACCE
ID HUTP_BACCE Reviewed; 132 AA.
AC Q8GCJ0;
DT 10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=Hut operon positive regulatory protein;
DE Flags: Fragment;
GN Name=hutP;
OS Bacillus cereus.
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=1396;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 53522 / UW85;
RX PubMed=12571047; DOI=10.1128/aem.69.2.1197-1205.2003;
RA Dunn A.K., Klimowicz A.K., Handelsman J.;
RT "Use of a promoter trap to identify Bacillus cereus genes regulated by
RT tomato seed exudate and a rhizosphere resident, Pseudomonas aureofaciens.";
RL Appl. Environ. Microbiol. 69:1197-1205(2003).
CC -!- FUNCTION: Antiterminator that binds to cis-acting regulatory sequences
CC on the mRNA in the presence of histidine, thereby suppressing
CC transcription termination and activating the hut operon for histidine
CC utilization. {ECO:0000250}.
CC -!- SUBUNIT: Homohexamer. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the HutP family. {ECO:0000305}.
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DR EMBL; AY169374; AAN87177.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8GCJ0; -.
DR SMR; Q8GCJ0; -.
DR STRING; 1396.DJ87_1291; -.
DR eggNOG; ENOG502ZFIH; Bacteria.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006547; P:histidine metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1510.10; -; 1.
DR InterPro; IPR015111; Regulatory_HutP.
DR InterPro; IPR036482; Regulatory_HutP_sf.
DR Pfam; PF09021; HutP; 1.
DR SUPFAM; SSF111064; SSF111064; 1.
PE 3: Inferred from homology;
KW Activator; Histidine metabolism; RNA-binding; Transcription;
KW Transcription regulation.
FT CHAIN 1..>132
FT /note="Hut operon positive regulatory protein"
FT /id="PRO_0000203788"
FT NON_TER 132
SQ SEQUENCE 132 AA; 14394 MW; DE79E06C12FF8E66 CRC64;
MLLQGTHRIG RMAMLLALAD ENESPVLSIP KGWKYCTGKV GSMNSQKVVA AMETAAKSNQ
VIETDVYRET HALYHAIMEA LYGVTRGQIQ LADVLRTVGL RFAIVRGTPY DGKKEGEWVA
VALYGTIGAP VK