ID   HV01_CANLF              Reviewed;         114 AA.
AC   P01784;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Ig heavy chain V region GOM;
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX   NCBI_TaxID=9615;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=407924; DOI=10.1021/bi00633a019;
RA   Wasserman R.L., Capra J.D.;
RT   "Primary structure of the variable regions of two canine immunoglobulin
RT   heavy chains.";
RL   Biochemistry 16:3160-3168(1977).
CC   -!- MISCELLANEOUS: This chain was isolated from a myeloma protein.
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DR   PIR; A02067; AVDGGM.
DR   AlphaFoldDB; P01784; -.
DR   SMR; P01784; -.
DR   PRIDE; P01784; -.
DR   Proteomes; UP000002254; Unplaced.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0042571; C:immunoglobulin complex, circulating; IBA:GO_Central.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0034987; F:immunoglobulin receptor binding; IBA:GO_Central.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0006958; P:complement activation, classical pathway; IBA:GO_Central.
DR   GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR   GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IBA:GO_Central.
DR   GO; GO:0006910; P:phagocytosis, recognition; IBA:GO_Central.
DR   GO; GO:0050871; P:positive regulation of B cell activation; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Adaptive immunity; Direct protein sequencing; Immunity; Immunoglobulin;
KW   Reference proteome.
FT   CHAIN           1..>114
FT                   /note="Ig heavy chain V region GOM"
FT                   /id="PRO_0000059856"
FT   DOMAIN          1..112
FT                   /note="Ig-like"
FT   NON_TER         114
SQ   SEQUENCE   114 AA;  12430 MW;  B1D4745D2C4E13C4 CRC64;
     EVQLVESGGD LVKPGGSLRL SCVASGITFS GYDMQWVRQA PGKGLQKVAY FNDALSAQGY
     ADAVKGRFTI SKDNAKDSLY LQMNSLRAED TAVYYCAPWQ FEYWGQGTLV TVSS