ID   HV01_XENLA              Reviewed;         136 AA.
AC   P20956;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Ig heavy chain V region XIG8;
DE   Flags: Precursor; Fragment;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2451244; DOI=10.1073/pnas.85.7.2245;
RA   Schwager J., Mikoryak C.A., Steiner L.A.;
RT   "Amino acid sequence of heavy chain from Xenopus laevis IgM deduced from
RT   cDNA sequence: implications for evolution of immunoglobulin domains.";
RL   Proc. Natl. Acad. Sci. U.S.A. 85:2245-2249(1988).
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DR   EMBL; M20484; AAA49774.1; ALT_TERM; mRNA.
DR   PIR; A31933; A31933.
DR   AlphaFoldDB; P20956; -.
DR   SMR; P20956; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   2: Evidence at transcript level;
KW   Adaptive immunity; Immunity; Immunoglobulin; Reference proteome; Signal.
FT   SIGNAL          <1..18
FT   CHAIN           19..136
FT                   /note="Ig heavy chain V region XIG8"
FT                   /id="PRO_0000015210"
FT   DOMAIN          19..128
FT                   /note="Ig-like"
FT   NON_TER         1
FT   NON_TER         136
SQ   SEQUENCE   136 AA;  15123 MW;  3141838981441963 CRC64;
     GFGIFVIFMF FSPSCILSQT LQESGPGTVK PSESLRLTCT VSGFELTSYY VYWIRQPPRK
     TLEWIGVVRT DGSTAIADSL KNRVTITKDN GKKQVYLQMN GMEVKDTAMY YCTSTLAGTA
     GYFEHWGQGT MVTVTS