ID   HV2B_RABIT              Reviewed;         117 AA.
AC   P01828;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   11-DEC-2019, entry version 69.
DE   RecName: Full=Ig heavy chain V-A2 region K-25;
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986;
RN   [1]
RP   PROTEIN SEQUENCE, AND PYROGLUTAMATE FORMATION AT GLN-1.
RX   PubMed=241319; DOI=10.1042/bj1470235;
RA   Jaton J.-C.;
RT   "Comparison of the amino acid sequences of the variable domains of two
RT   homogeneous rabbit antibodies to type III pneumococcal polysaccharide.";
RL   Biochem. J. 147:235-247(1975).
CC   -!- MISCELLANEOUS: This chain was obtained from antibody to type III
CC       pneumococci and was isolated from the serum of a single rabbit.
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DR   PIR; A02104; GARB2K.
DR   Proteomes; UP000001811; Unplaced.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Adaptive immunity; Direct protein sequencing; Disulfide bond; Immunity;
KW   Immunoglobulin; Pyrrolidone carboxylic acid; Reference proteome.
FT   CHAIN           1..>117
FT                   /note="Ig heavy chain V-A2 region K-25"
FT                   /id="PRO_0000059937"
FT   DOMAIN          1..106
FT                   /note="Ig-like"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:241319"
FT   DISULFID        21..91
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114,
FT                   ECO:0000269|PubMed:241319"
FT   NON_TER         117
SQ   SEQUENCE   117 AA;  12580 MW;  28DD87FDB7AEE9B8 CRC64;
     QSVKESEGGL FKPTDTLTLT CTVSGFSLSG YDMSWVRQAP GKGLEWIGVI YASGSTYYAT
     WAKSRSTITR TSBTVBLMDS LTAQDTATYF CARGHTGLSY LKSSVDVWGP GTLVTVS