ID   HVC1_HETFR              Reviewed;         370 AA.
AC   P23084;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Ig heavy chain C region;
DE   AltName: Full=Clone 6125;
DE   Flags: Fragment;
OS   Heterodontus francisci (Horn shark) (Cestracion francisci).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Heterodontoidea; Heterodontiformes;
OC   Heterodontidae; Heterodontus.
OX   NCBI_TaxID=7792;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3138109; DOI=10.1002/j.1460-2075.1988.tb03036.x;
RA   Kokubu F., Hinds K., Litman R., Shamblott M.J., Litman G.W.;
RT   "Complete structure and organization of immunoglobulin heavy chain constant
RT   region genes in a phylogenetically primitive vertebrate.";
RL   EMBO J. 7:1979-1988(1988).
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DR   EMBL; X07783; CAA30616.1; -; mRNA.
DR   PIR; S01851; HVRKC5.
DR   AlphaFoldDB; P23084; -.
DR   SMR; P23084; -.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   Pfam; PF07654; C1-set; 3.
DR   SMART; SM00407; IGc1; 3.
DR   SUPFAM; SSF48726; SSF48726; 3.
DR   PROSITE; PS50835; IG_LIKE; 3.
DR   PROSITE; PS00290; IG_MHC; 3.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Immunoglobulin domain; Repeat.
FT   CHAIN           <1..370
FT                   /note="Ig heavy chain C region"
FT                   /id="PRO_0000153629"
FT   DOMAIN          40..134
FT                   /note="Ig-like 1"
FT   DOMAIN          145..237
FT                   /note="Ig-like 2"
FT   DOMAIN          247..347
FT                   /note="Ig-like 3"
FT   CARBOHYD        98
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        132
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        177
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        343
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        347
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        357
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   NON_TER         1
SQ   SEQUENCE   370 AA;  40587 MW;  32833A6EFE7ADED0 CRC64;
     SQLTITDSEV GSSKIYCEVR RGESLWIKEI PDCKGDIVHP TVILTQTSSE EITSSRFATV
     VCSIIDFHPE AITVNWLKDG HPMESGFVTS PACETNGNFS ATSRLTVPAR EWFTNTVYTC
     QVSHQAATQS RNITGSPDSS ECNHPAIKLL PPSIEQVLLE ATVTLTCVVS NAPYGVNVSW
     TQEQKPLKSE IAVQPGEDPD SVISTVDIST QAWLSEAVFY CVVSHQDLPT PLRDSIHKEA
     WKDLREPSVS VLLPPAEEIS AERFLSLTCL VRGFSPREIF VKWTVNDKSV NPGNYKNTEV
     MAENDKSSFF IYSLLSIAAE EWASGASYSC VVGHEAIPLK IINRTVNKSS GKPSFVNISL
     ALLDTVNSCQ