ID   HVC2_HETFR              Reviewed;         438 AA.
AC   P23085;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Ig heavy chain C region;
DE   AltName: Full=Clone 12022;
DE   Flags: Fragment;
OS   Heterodontus francisci (Horn shark) (Cestracion francisci).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Heterodontoidea; Heterodontiformes;
OC   Heterodontidae; Heterodontus.
OX   NCBI_TaxID=7792;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3138109; DOI=10.1002/j.1460-2075.1988.tb03036.x;
RA   Kokubu F., Hinds K., Litman R., Shamblott M.J., Litman G.W.;
RT   "Complete structure and organization of immunoglobulin heavy chain constant
RT   region genes in a phylogenetically primitive vertebrate.";
RL   EMBO J. 7:1979-1988(1988).
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DR   EMBL; X07784; CAA30617.1; -; mRNA.
DR   PIR; S00980; HVRKC2.
DR   AlphaFoldDB; P23085; -.
DR   SMR; P23085; -.
DR   Gene3D; 2.60.40.10; -; 4.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   Pfam; PF07654; C1-set; 4.
DR   SMART; SM00407; IGc1; 4.
DR   SUPFAM; SSF48726; SSF48726; 4.
DR   PROSITE; PS50835; IG_LIKE; 4.
DR   PROSITE; PS00290; IG_MHC; 3.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Immunoglobulin domain; Repeat.
FT   CHAIN           <1..438
FT                   /note="Ig heavy chain C region"
FT                   /id="PRO_0000153630"
FT   DOMAIN          5..101
FT                   /note="Ig-like 1"
FT   DOMAIN          108..202
FT                   /note="Ig-like 2"
FT   DOMAIN          213..305
FT                   /note="Ig-like 3"
FT   DOMAIN          315..415
FT                   /note="Ig-like 4"
FT   CARBOHYD        166
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        200
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        245
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        275
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        374
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        411
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        415
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        425
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   NON_TER         1
SQ   SEQUENCE   438 AA;  47904 MW;  6E67A9C5BBF7AA7B CRC64;
     ATPSPAILYG LCSCEQTNTD GSLAYGCLAM DYSPEITSIT WKKDKEPITT GLKIYPSVLN
     KKGTYTRSSQ LTITESEVGS SKIYCEVRRG ESLWIKEILD CKGDIVPPTV ILTQSSSEEI
     TSRRFATVLC SIIDFHPESI TVSWLKDGQP MDSGFVTSPT CEVNGNFSAT SRLTVPAGEW
     FSNTVYTCQV AHQEVTQSRN ITGSQVPCSI GDPVIKLLPP SIEQVLLEAT VTLTCVVSNA
     PYGVNVSWTQ EKKPLKSEIA VQPGEDSDSV ISTVNISTQA WLSGAEFYCV VSHQDLPTPL
     RASIHKEEVK DLREPFVSVL LPPAEDVSAQ RFLSLTCLVR GFSPREIFIK WTVNDKSVNP
     GNYKNTEVMA ENDNRSFFIY SLLSIAAEEW ASGASYSCVV GHEAIPLKII NRTVNKSSGK
     PSFVNISLAL LDTVNSCQ