HVM32_MOUSE
ID HVM32_MOUSE Reviewed; 115 AA.
AC P01801;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Ig heavy chain V-III region J606;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=6798111;
RA Johnson N., Slankard J., Paul L., Hood L.;
RT "The complete V domain amino acid sequences of two myeloma inulin-binding
RT proteins.";
RL J. Immunol. 128:302-307(1982).
CC -!- MISCELLANEOUS: This chain was isolated from a myeloma protein that
CC binds inulin.
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DR PIR; C92811; AVMS06.
DR PDB; 1M71; X-ray; 2.80 A; B=1-114.
DR PDB; 1M7D; X-ray; 2.30 A; B=1-114.
DR PDB; 1M7I; X-ray; 2.50 A; B=1-114.
DR PDB; 1PZ5; X-ray; 1.80 A; B=1-114.
DR PDB; 1SM3; X-ray; 1.95 A; H=2-114.
DR PDB; 2DLF; X-ray; 1.55 A; H=1-115.
DR PDB; 5A2I; X-ray; 1.88 A; H=6-99, H=102-115.
DR PDB; 5A2J; X-ray; 1.65 A; H=6-115.
DR PDB; 5A2K; X-ray; 1.70 A; H=6-99, H=102-115.
DR PDB; 5A2L; X-ray; 1.79 A; H=6-115.
DR PDB; 5N7B; X-ray; 1.70 A; H=1-114.
DR PDB; 5OWP; X-ray; 1.85 A; H=6-111.
DR PDBsum; 1M71; -.
DR PDBsum; 1M7D; -.
DR PDBsum; 1M7I; -.
DR PDBsum; 1PZ5; -.
DR PDBsum; 1SM3; -.
DR PDBsum; 2DLF; -.
DR PDBsum; 5A2I; -.
DR PDBsum; 5A2J; -.
DR PDBsum; 5A2K; -.
DR PDBsum; 5A2L; -.
DR PDBsum; 5N7B; -.
DR PDBsum; 5OWP; -.
DR AlphaFoldDB; P01801; -.
DR SMR; P01801; -.
DR MINT; P01801; -.
DR MaxQB; P01801; -.
DR PRIDE; P01801; -.
DR EvolutionaryTrace; P01801; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P01801; protein.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0042571; C:immunoglobulin complex, circulating; IBA:GO_Central.
DR GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR GO; GO:0034987; F:immunoglobulin receptor binding; IBA:GO_Central.
DR GO; GO:0050853; P:B cell receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0006958; P:complement activation, classical pathway; IBA:GO_Central.
DR GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR GO; GO:0006911; P:phagocytosis, engulfment; IBA:GO_Central.
DR GO; GO:0006910; P:phagocytosis, recognition; IBA:GO_Central.
DR GO; GO:0050871; P:positive regulation of B cell activation; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Adaptive immunity; Direct protein sequencing; Disulfide bond;
KW Immunity; Immunoglobulin; Reference proteome.
FT CHAIN 1..>115
FT /note="Ig heavy chain V-III region J606"
FT /id="PRO_0000059886"
FT DOMAIN 1..114
FT /note="Ig-like"
FT DISULFID 22..98
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT NON_TER 115
FT STRAND 3..7
FT /evidence="ECO:0007829|PDB:2DLF"
FT STRAND 10..12
FT /evidence="ECO:0007829|PDB:5A2J"
FT STRAND 18..27
FT /evidence="ECO:0007829|PDB:2DLF"
FT HELIX 29..31
FT /evidence="ECO:0007829|PDB:2DLF"
FT STRAND 33..40
FT /evidence="ECO:0007829|PDB:2DLF"
FT TURN 41..43
FT /evidence="ECO:0007829|PDB:2DLF"
FT STRAND 44..51
FT /evidence="ECO:0007829|PDB:2DLF"
FT HELIX 54..56
FT /evidence="ECO:0007829|PDB:2DLF"
FT STRAND 60..62
FT /evidence="ECO:0007829|PDB:2DLF"
FT TURN 64..69
FT /evidence="ECO:0007829|PDB:2DLF"
FT STRAND 70..75
FT /evidence="ECO:0007829|PDB:2DLF"
FT TURN 76..79
FT /evidence="ECO:0007829|PDB:2DLF"
FT STRAND 80..85
FT /evidence="ECO:0007829|PDB:2DLF"
FT HELIX 90..92
FT /evidence="ECO:0007829|PDB:2DLF"
FT STRAND 94..102
FT /evidence="ECO:0007829|PDB:2DLF"
FT STRAND 103..105
FT /evidence="ECO:0007829|PDB:5OWP"
FT STRAND 109..113
FT /evidence="ECO:0007829|PDB:2DLF"
SQ SEQUENCE 115 AA; 12810 MW; B67AD6638A121A5F CRC64;
EVKLEESGGG LVQPGGSMKL SCVASGFTFS NYWMNWVRQS PEKGLEWVAE IRLKSNNYAT
HYAESVKGRF TISRDDSKSS VYLQMNNLRA EDTGIYYCTT GFAYWGQGTL VTVSA
