HVM35_MOUSE
ID HVM35_MOUSE Reviewed; 111 AA.
AC P01804;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Ig heavy chain V-III region HPC76;
DE Flags: Fragment;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=6251474; DOI=10.1073/pnas.77.6.3630;
RA Bernard O., Gough N.M.;
RT "Nucleotide sequence of immunoglobulin heavy chain joining segments between
RT translocated VH and mu constant regions genes.";
RL Proc. Natl. Acad. Sci. U.S.A. 77:3630-3634(1980).
CC -!- MISCELLANEOUS: The sequence of the first 197 residues of the C region
CC was also determined and differs in only 3 positions from the
CC corresponding portion of the mouse MOPC 104e mu chain.
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DR PIR; A02074; MHMS76.
DR AlphaFoldDB; P01804; -.
DR SMR; P01804; -.
DR MaxQB; P01804; -.
DR PRIDE; P01804; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P01804; protein.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0042571; C:immunoglobulin complex, circulating; IBA:GO_Central.
DR GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR GO; GO:0034987; F:immunoglobulin receptor binding; IBA:GO_Central.
DR GO; GO:0050853; P:B cell receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0006958; P:complement activation, classical pathway; IBA:GO_Central.
DR GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR GO; GO:0006911; P:phagocytosis, engulfment; IBA:GO_Central.
DR GO; GO:0006910; P:phagocytosis, recognition; IBA:GO_Central.
DR GO; GO:0050871; P:positive regulation of B cell activation; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Adaptive immunity; Immunity; Immunoglobulin; Reference proteome.
FT CHAIN <1..>111
FT /note="Ig heavy chain V-III region HPC76"
FT /id="PRO_0000059889"
FT DOMAIN <1..110
FT /note="Ig-like"
FT NON_TER 1
FT NON_TER 111
SQ SEQUENCE 111 AA; 12304 MW; 0EDE98EC7348056A CRC64;
ESGGGLVQPG GSMKLSCVAS GFTFSNYWMN WVRQSPEKGL EWVAEIRLKS GYATHYAESV
KGRFTISRDD SKSSVYLQMN NLRAEDTGIY YCTRPGVPDY WGQGTTLTVS S