ID   HVM41_MOUSE             Reviewed;         117 AA.
AC   P01811;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Ig heavy chain V region UPC10;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=6181731;
RA   Auffray C., Sikorav J.-L., Ollo R., Rougeon F.;
RT   "Correlation between D region structure and antigen-binding specificity:
RT   evidences from the comparison of closely related immunoglobulin VH
RT   sequences.";
RL   Ann. Immunol. (Paris) 132D:77-88(1981).
CC   -!- MISCELLANEOUS: This chain was isolated from an Ig gamma-2a myeloma
CC       protein binding 2,6-levan.
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DR   EMBL; M36631; AAA38078.1; -; mRNA.
DR   PIR; A02081; G2MSU1.
DR   PDB; 1UZ6; X-ray; 2.05 A; F/H/P/W=1-117.
DR   PDB; 1UZ8; X-ray; 1.80 A; B/H=1-117.
DR   PDBsum; 1UZ6; -.
DR   PDBsum; 1UZ8; -.
DR   AlphaFoldDB; P01811; -.
DR   SMR; P01811; -.
DR   MaxQB; P01811; -.
DR   PRIDE; P01811; -.
DR   EvolutionaryTrace; P01811; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01811; protein.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0042571; C:immunoglobulin complex, circulating; IBA:GO_Central.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0034987; F:immunoglobulin receptor binding; IBA:GO_Central.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0006958; P:complement activation, classical pathway; IBA:GO_Central.
DR   GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR   GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IBA:GO_Central.
DR   GO; GO:0006910; P:phagocytosis, recognition; IBA:GO_Central.
DR   GO; GO:0050871; P:positive regulation of B cell activation; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Adaptive immunity; Immunity; Immunoglobulin;
KW   Reference proteome.
FT   CHAIN           1..>117
FT                   /note="Ig heavy chain V region UPC10"
FT                   /id="PRO_0000059894"
FT   DOMAIN          1..116
FT                   /note="Ig-like"
FT   NON_TER         117
SQ   SEQUENCE   117 AA;  13001 MW;  B20A1074F8E99E7F CRC64;
     EVKLLESGGG LVQPGGSLKL SCAASGFDFS GYWMSWVRQA PGKGLEWIGE INPDSSTINY
     TPFLKDKFII SRDNAKNTLF LQMSKVRSED TALYFCARNW DVGFDYWGQV TTLTVSS