HVM57_MOUSE
ID HVM57_MOUSE Reviewed; 98 AA.
AC P18528;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1990, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Ig heavy chain V region 6.96;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BALB/cJ;
RX PubMed=2499654; DOI=10.1084/jem.169.6.2007;
RA Levy N.S., Malipiero U.V., Lebecque S.G., Gearhart P.J.;
RT "Early onset of somatic mutation in immunoglobulin VH genes during the
RT primary immune response.";
RL J. Exp. Med. 169:2007-2019(1989).
CC -!- MISCELLANEOUS: This sequence belongs to the VH7183 subfamily.
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DR PIR; JT0501; HVMS96.
DR AlphaFoldDB; P18528; -.
DR SMR; P18528; -.
DR MINT; P18528; -.
DR MaxQB; P18528; -.
DR PRIDE; P18528; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P18528; protein.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0042571; C:immunoglobulin complex, circulating; IBA:GO_Central.
DR GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR GO; GO:0034987; F:immunoglobulin receptor binding; IBA:GO_Central.
DR GO; GO:0050853; P:B cell receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0006958; P:complement activation, classical pathway; IBA:GO_Central.
DR GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR GO; GO:0006911; P:phagocytosis, engulfment; IBA:GO_Central.
DR GO; GO:0006910; P:phagocytosis, recognition; IBA:GO_Central.
DR GO; GO:0050871; P:positive regulation of B cell activation; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Adaptive immunity; Immunity; Immunoglobulin; Reference proteome.
FT CHAIN 1..>98
FT /note="Ig heavy chain V region 6.96"
FT /id="PRO_0000059900"
FT DOMAIN 1..>98
FT /note="Ig-like"
FT NON_TER 98
SQ SEQUENCE 98 AA; 11007 MW; B8644F7F92FBF95B CRC64;
EVQLVESGGG LVKPGGSLKL SCAASGFTFS DYYMYWVRQT PEKRLEWVAT ISDGGSYTYY
PDSVKGRFTI SRDNAKNNLY LQMSSLKSED TAMYYCAR