ID   HVRB_RHOCB              Reviewed;         292 AA.
AC   P42507; D5AKH0;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=AhcY transcriptional activator HvrB;
GN   Name=hvrB; OrderedLocusNames=RCAP_rcc00047;
OS   Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=272942;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX   PubMed=8282711; DOI=10.1128/jb.176.1.61-69.1994;
RA   Buggy J.J., Sganga M.W., Bauer C.E.;
RT   "Nucleotide sequence and characterization of the Rhodobacter capsulatus
RT   hvrB gene: HvrB is an activator of S-adenosyl-L-homocysteine hydrolase
RT   expression and is a member of the LysR family.";
RL   J. Bacteriol. 176:61-69(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX   PubMed=20418398; DOI=10.1128/jb.00366-10;
RA   Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V.,
RA   Haselkorn R.;
RT   "Complete genome sequence of the photosynthetic purple nonsulfur bacterium
RT   Rhodobacter capsulatus SB 1003.";
RL   J. Bacteriol. 192:3545-3546(2010).
CC   -!- FUNCTION: Functions as a low-light activator of ahcY expression (gene
CC       for S-adenosyl-L-homocysteine hydrolase) and as a high-light activator
CC       of an uncharacterized 21.6 kDa protein in the ahcY-hvrB intergenic
CC       region (orf5). It is also a negative regulator of its own expression.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; L23836; AAA53542.1; -; Genomic_DNA.
DR   EMBL; CP001312; ADE83812.1; -; Genomic_DNA.
DR   PIR; C36863; C36863.
DR   AlphaFoldDB; P42507; -.
DR   SMR; P42507; -.
DR   STRING; 272942.RCAP_rcc00047; -.
DR   EnsemblBacteria; ADE83812; ADE83812; RCAP_rcc00047.
DR   KEGG; rcp:RCAP_rcc00047; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_37_1_5; -.
DR   OMA; FAVWWLM; -.
DR   Proteomes; UP000002361; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..292
FT                   /note="AhcY transcriptional activator HvrB"
FT                   /id="PRO_0000105639"
FT   DOMAIN          10..67
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        27..46
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   292 AA;  32174 MW;  782CCC27EE101A6A CRC64;
     MSEIDWRKMP PLTALRAFAA TASEGGFSAA ARKLNVTHAA IAQQVRALEA DLDVPLVWRD
     GKHLHLTPEG ERFAKALADG FSMIQSAADM LRADTSEKAL TVTVPPVFAS EWLMPRLARF
     WKKHPDIPLS LLPDARLVDL KEIGANIGIR FGVGKWPGVI SVFLTAAPQV VVAAPELLGG
     RKKLSLREMA MLPWVREGDW PEQMQLLESM GLVPAALKFV DFPNEELALA AAREGIGLHL
     ETEALIVEDL KLGWLVKIHE LTEESLGYYI VRPPGRLNPA AKIFIDWLKA EA