HXA5_SALSA
ID HXA5_SALSA Reviewed; 78 AA.
AC P09637;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1990, sequence version 2.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Homeobox protein Hox-A5;
DE AltName: Full=S12-B;
DE Flags: Fragment;
GN Name=hoxa5;
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2897318; DOI=10.1016/0378-1119(88)90588-4;
RA Fjose A., Molven A., Eiken H.G.;
RT "Molecular cloning and characterization of homeo-box-containing genes from
RT Atlantic salmon.";
RL Gene 62:141-152(1988).
CC -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC developmental regulatory system that provides cells with specific
CC positional identities on the anterior-posterior axis.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the Antp homeobox family. {ECO:0000305}.
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DR EMBL; M18904; AAA49560.1; -; Genomic_DNA.
DR PIR; I51342; I51342.
DR AlphaFoldDB; P09637; -.
DR SMR; P09637; -.
DR STRING; 8030.ENSSSAP00000075091; -.
DR Proteomes; UP000087266; Genome assembly.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN <1..78
FT /note="Homeobox protein Hox-A5"
FT /id="PRO_0000200065"
FT DNA_BIND 1..60
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT NON_TER 1
SQ SEQUENCE 78 AA; 9489 MW; 828DEBDDF78AC820 CRC64;
GRGRGQTYTR YQTLELEKEF HFNRYLTRRR RIEMAHALCL SERQIKIWFQ NRRMKWKKDN
KLKSMSMAAA GGVGYHRP