ID   HXA7_MORSA              Reviewed;         225 AA.
AC   Q9PWD4;
DT   11-JUL-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Homeobox protein Hox-A7;
GN   Name=hoxa7;
OS   Morone saxatilis (Striped bass) (Perca saxatilis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Moronidae; Morone.
OX   NCBI_TaxID=34816;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10327649;
RX   DOI=10.1002/(sici)1097-010x(19990415)285:1<41::aid-jez5>3.0.co;2-d;
RA   Snell E.A., Scemama J.L., Stellwag E.J.;
RT   "Genomic organization of the Hoxa4-Hoxa10 region from Morone saxatilis:
RT   implications for Hox gene evolution among vertebrates.";
RL   J. Exp. Zool. 285:41-49(1999).
CC   -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC       developmental regulatory system that provides cells with specific
CC       positional identities on the anterior-posterior axis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC   -!- SIMILARITY: Belongs to the Antp homeobox family. {ECO:0000305}.
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DR   EMBL; AF089743; AAD46397.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9PWD4; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017995; Homeobox_antennapedia.
DR   InterPro; IPR001827; Homeobox_Antennapedia_CS.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00025; ANTENNAPEDIA.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00032; ANTENNAPEDIA; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   3: Inferred from homology;
KW   Developmental protein; DNA-binding; Homeobox; Nucleus; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..225
FT                   /note="Homeobox protein Hox-A7"
FT                   /id="PRO_0000200078"
FT   DNA_BIND        126..185
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          183..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           115..120
FT                   /note="Antp-type hexapeptide"
FT   COMPBIAS        201..216
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   225 AA;  25677 MW;  C89FDEABA77F7CBC CRC64;
     MSSYYVDGLL SKYTAGSSLF PNVERASCSI GPSGEDYGSA RTTAAIAFAP SLSGVYSVSD
     AVYQSRPVFT SGYGQGQDAH TLHCSLFDQS RLFTDSCCHP EPGPLTSPPD KQYRMYPWMR
     ASDPTRKRGR QTYSRYQTLE LEKEFHFNRY LTRRRRIEIA HALCLSERQI KIWFQNRRMK
     WKKDHKEEPV STPSGEKDCD IQPVSEAEEP KAVNNPERRF GVRNG