HXA9_CHICK
ID HXA9_CHICK Reviewed; 169 AA.
AC Q98924;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Homeobox protein Hox-A9;
DE Flags: Fragment;
GN Name=HOXA9;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Embryo;
RX PubMed=8922526;
RX DOI=10.1002/(sici)1097-0177(199611)207:3<270::aid-aja4>3.0.co;2-e;
RA Gaunt S.J., Strachan L.;
RT "Temporal colinearity in expression of anterior Hox genes in developing
RT chick embryos.";
RL Dev. Dyn. 207:270-280(1996).
CC -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC developmental regulatory system that provides cells with specific
CC positional identities on the anterior-posterior axis.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the Abd-B homeobox family. {ECO:0000305}.
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DR EMBL; X97750; CAA66331.1; -; mRNA.
DR AlphaFoldDB; Q98924; -.
DR SMR; Q98924; -.
DR STRING; 9031.ENSGALP00000018012; -.
DR PaxDb; Q98924; -.
DR VEuPathDB; HostDB:geneid_396096; -.
DR eggNOG; KOG0487; Eukaryota.
DR InParanoid; Q98924; -.
DR PhylomeDB; Q98924; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009952; P:anterior/posterior pattern specification; IBA:GO_Central.
DR GO; GO:0048704; P:embryonic skeletal system morphogenesis; IBA:GO_Central.
DR GO; GO:0009954; P:proximal/distal pattern formation; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR006711; Hox9_activation_N.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF04617; Hox9_act; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN <1..169
FT /note="Homeobox protein Hox-A9"
FT /id="PRO_0000200083"
FT DNA_BIND 103..162
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 52..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
SQ SEQUENCE 169 AA; 19668 MW; 9D74877543924B87 CRC64;
DGRYMRSWLE PVPGSLSFPG LPTSRHYGIK PEPLAARRGD CTTFDTHTLS LSDLPCGSPP
VDRDKQSHEG AFSENNGESE ANGEKPHIDP NNPAANWLHA RSTRKKRCPY TKHQTLELEK
EFLFNMYLTR DRRYEVARLL NLTERQVKIW FQNRRMKMKK INKDRAKDE
