ID   HXA9_MORSA              Reviewed;         269 AA.
AC   Q9PWD5;
DT   11-JUL-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Homeobox protein Hox-A9;
GN   Name=hoxa9;
OS   Morone saxatilis (Striped bass) (Perca saxatilis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Moronidae; Morone.
OX   NCBI_TaxID=34816;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10327649;
RX   DOI=10.1002/(sici)1097-010x(19990415)285:1<41::aid-jez5>3.0.co;2-d;
RA   Snell E.A., Scemama J.L., Stellwag E.J.;
RT   "Genomic organization of the Hoxa4-Hoxa10 region from Morone saxatilis:
RT   implications for Hox gene evolution among vertebrates.";
RL   J. Exp. Zool. 285:41-49(1999).
CC   -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC       developmental regulatory system that provides cells with specific
CC       positional identities on the anterior-posterior axis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC   -!- SIMILARITY: Belongs to the Abd-B homeobox family. {ECO:0000305}.
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DR   EMBL; AF089743; AAD46396.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9PWD5; -.
DR   SMR; Q9PWD5; -.
DR   PRIDE; Q9PWD5; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   InterPro; IPR006711; Hox9_activation_N.
DR   InterPro; IPR017112; HXA9/HXB9/HXC9.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF04617; Hox9_act; 1.
DR   PIRSF; PIRSF037109; Homeobox_Hox9; 1.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   3: Inferred from homology;
KW   Developmental protein; DNA-binding; Homeobox; Nucleus; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..269
FT                   /note="Homeobox protein Hox-A9"
FT                   /id="PRO_0000200088"
FT   DNA_BIND        202..261
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          159..192
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   269 AA;  29600 MW;  8D49DCE0597D2A4C CRC64;
     MSTSGTLTSY YVDSLILPES EELSVPRYPS GPGLQHARQS ASISDHSELG TCTFPSKPPV
     FGPSWSHVPA QFPGTVSSVY HHHYGHPQGP VGADTDGRYQ SWLLEPMSGS LPMAGLPTTH
     HYGIKPEGLG TRADGALPGS HTALLLSDYA NGTVATASPV EKDTLSGQAG DVSGEAEEKP
     GLDPSKSLQN NPVSNWLHAS ATRKKRCPYT KHQILELEKE FLFNTYLTRD RRYEVARLLN
     LTERQVKIWF QNRRMKMKKF NKDGAPKDE