ID   HXB1_CYPCA              Reviewed;         315 AA.
AC   Q90346; Q90345;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Homeobox protein Hox-B1;
GN   Name=hoxb1;
OS   Cyprinus carpio (Common carp).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Cyprininae; Cyprinus.
OX   NCBI_TaxID=7962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8793616;
RA   Stevens C.J.M., Samallo J., Schipper H., Stroband H.W.J., Te Kronnie G.;
RT   "Expression of Hoxb-1 during gastrulation and segmentation stages of carp
RT   (Cyprinus carpio).";
RL   Int. J. Dev. Biol. 40:463-470(1996).
CC   -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC       developmental regulatory system that provides cells with specific
CC       positional identities on the anterior-posterior axis. Acts on the
CC       anterior body structures (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the Antp homeobox family. Labial subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA62553.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; X91079; CAA62554.1; -; mRNA.
DR   EMBL; X91079; CAA62553.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; Q90346; -.
DR   SMR; Q90346; -.
DR   Proteomes; UP000694384; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   InterPro; IPR046327; HXA1/B1/D1.
DR   PANTHER; PTHR45946; PTHR45946; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..315
FT                   /note="Homeobox protein Hox-B1"
FT                   /id="PRO_0000200112"
FT   DNA_BIND        221..280
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          177..200
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          272..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           197..202
FT                   /note="Antp-type hexapeptide"
SQ   SEQUENCE   315 AA;  34781 MW;  96274EC6D4213322 CRC64;
     MDNSSMNSFL EYTICNRGTN AYSPKAGYQH LDQALSGPFH TGHARYSHNA DGRLYIGGSN
     QPAAAQHQHQ SGVYAHHQHQ THQSGIGLTY GGTGTTSYGT QACANPDYAQ HQYFINPEQD
     GMYYHSSGFS NSNLGPHYGS MAGAYCGAQG AVPAAPYQHH GCEGQDHQRG YSQGTYADLS
     RSQGRERDTD QSPPGKTFDW MKVKRNPPKT AKVADYGLGP QNTIRTNFTT KQLTELEKEF
     HFSKYLTRAR RVEIAATLEL NETQVKIWFQ NRRMKQKKRE KEGLAPASST LSKDLEDHSD
     HSTSTSPGAS PSPDS