ID   HXB3_XENLA              Reviewed;          60 AA.
AC   P31247;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Homeobox protein Hox-B3;
DE   AltName: Full=XlHox-2.7;
DE   Flags: Fragment;
GN   Name=hoxb3;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1384809; DOI=10.1002/aja.1001940104;
RA   Leroy P., De Robertis E.M.;
RT   "Effects of lithium chloride and retinoic acid on the expression of genes
RT   from the Xenopus laevis Hox 2 complex.";
RL   Dev. Dyn. 194:21-32(1992).
CC   -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC       developmental regulatory system that provides cells with specific
CC       positional identities on the anterior-posterior axis.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the Antp homeobox family. {ECO:0000305}.
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DR   EMBL; M91588; AAA49751.1; -; mRNA.
DR   PIR; I51440; I51440.
DR   AlphaFoldDB; P31247; -.
DR   SMR; P31247; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           <1..>60
FT                   /note="Homeobox protein Hox-B3"
FT                   /id="PRO_0000200121"
FT   DNA_BIND        1..60
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   NON_TER         1
FT   NON_TER         60
SQ   SEQUENCE   60 AA;  7491 MW;  D78624EE8EF8036B CRC64;
     SKRARTAYTS AQLVELEKEF HFNRYLCRPR RVEMANLLNL SERQIKIWFQ NRRMKYKKDQ