ID   HXD9_CHICK              Reviewed;          60 AA.
AC   P24340;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Homeobox protein Hox-D9;
DE   AltName: Full=Homeobox protein Hox-4.4;
DE            Short=Chox-4.4;
DE   Flags: Fragment;
GN   Name=HOXD9; Synonyms=CHOX-4.4;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=1673231; DOI=10.1038/350585a0;
RA   Izpisua-Belmonte J.-C., Tickle C., Dolle P., Wolpert L., Duboule D.;
RT   "Expression of the homeobox Hox-4 genes and the specification of position
RT   in chick wing development.";
RL   Nature 350:585-589(1991).
CC   -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC       developmental regulatory system that provides cells with specific
CC       positional identities on the anterior-posterior axis.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- DEVELOPMENTAL STAGE: HOXD genes are coordinately expressed in partially
CC       overlapping domains during wing development.
CC   -!- SIMILARITY: Belongs to the Abd-B homeobox family. {ECO:0000305}.
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DR   PIR; S14797; S14797.
DR   AlphaFoldDB; P24340; -.
DR   SMR; P24340; -.
DR   STRING; 9031.ENSGALP00000029264; -.
DR   PaxDb; P24340; -.
DR   VEuPathDB; HostDB:geneid_396096; -.
DR   eggNOG; KOG0487; Eukaryota.
DR   InParanoid; P24340; -.
DR   PhylomeDB; P24340; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IBA:GO_Central.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IBA:GO_Central.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           <1..>60
FT                   /note="Homeobox protein Hox-D9"
FT                   /id="PRO_0000200222"
FT   DNA_BIND        1..60
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   NON_TER         1
FT   NON_TER         60
SQ   SEQUENCE   60 AA;  7709 MW;  16733C16E919F682 CRC64;
     TRKKRCPYTK YQTLELEKEF LFNMYLTRDR RYEVARILNL TERQVKIWFQ NRRMKMKKMS