HYAE_ECOLI
ID HYAE_ECOLI Reviewed; 132 AA.
AC P19931;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Hydrogenase-1 operon protein HyaE;
GN Name=hyaE; OrderedLocusNames=b0976, JW0958;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2180913; DOI=10.1128/jb.172.4.1969-1977.1990;
RA Menon N.K., Robbins J., Peck H.D. Jr., Chatelus C.Y., Choi E.-S.,
RA Przybyla A.E.;
RT "Cloning and sequencing of a putative Escherichia coli [NiFe] hydrogenase-1
RT operon containing six open reading frames.";
RL J. Bacteriol. 172:1969-1977(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Not known. Could form, along with HyaD, a complex involved in
CC the processing of the hydrogenase 1 structural operon.
CC -!- SIMILARITY: Belongs to the HupG/HyaE family. {ECO:0000305}.
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DR EMBL; M34825; AAA24001.1; -; Genomic_DNA.
DR EMBL; U00096; AAC74061.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35741.1; -; Genomic_DNA.
DR PIR; JV0076; QQECHE.
DR RefSeq; NP_415495.1; NC_000913.3.
DR RefSeq; WP_000063978.1; NZ_LN832404.1.
DR PDB; 2HFD; NMR; -; A=1-132.
DR PDBsum; 2HFD; -.
DR AlphaFoldDB; P19931; -.
DR BMRB; P19931; -.
DR SMR; P19931; -.
DR BioGRID; 4260046; 21.
DR DIP; DIP-9961N; -.
DR IntAct; P19931; 11.
DR STRING; 511145.b0976; -.
DR jPOST; P19931; -.
DR PaxDb; P19931; -.
DR PRIDE; P19931; -.
DR EnsemblBacteria; AAC74061; AAC74061; b0976.
DR EnsemblBacteria; BAA35741; BAA35741; BAA35741.
DR GeneID; 945573; -.
DR KEGG; ecj:JW0958; -.
DR KEGG; eco:b0976; -.
DR PATRIC; fig|1411691.4.peg.1298; -.
DR EchoBASE; EB0467; -.
DR eggNOG; COG1999; Bacteria.
DR HOGENOM; CLU_144855_1_0_6; -.
DR InParanoid; P19931; -.
DR OMA; WHIAMAD; -.
DR PhylomeDB; P19931; -.
DR BioCyc; EcoCyc:EG10472-MON; -.
DR EvolutionaryTrace; P19931; -.
DR PRO; PR:P19931; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR CDD; cd02965; HyaE; 1.
DR InterPro; IPR010893; NiFe-hyd_mat_HyaE.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR Pfam; PF07449; HyaE; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome.
FT CHAIN 1..132
FT /note="Hydrogenase-1 operon protein HyaE"
FT /id="PRO_0000201414"
FT HELIX 6..15
FT /evidence="ECO:0007829|PDB:2HFD"
FT TURN 16..18
FT /evidence="ECO:0007829|PDB:2HFD"
FT STRAND 20..22
FT /evidence="ECO:0007829|PDB:2HFD"
FT HELIX 24..33
FT /evidence="ECO:0007829|PDB:2HFD"
FT STRAND 35..41
FT /evidence="ECO:0007829|PDB:2HFD"
FT STRAND 49..52
FT /evidence="ECO:0007829|PDB:2HFD"
FT HELIX 56..62
FT /evidence="ECO:0007829|PDB:2HFD"
FT STRAND 70..75
FT /evidence="ECO:0007829|PDB:2HFD"
FT HELIX 77..87
FT /evidence="ECO:0007829|PDB:2HFD"
FT STRAND 94..99
FT /evidence="ECO:0007829|PDB:2HFD"
FT STRAND 102..107
FT /evidence="ECO:0007829|PDB:2HFD"
FT HELIX 113..124
FT /evidence="ECO:0007829|PDB:2HFD"
SQ SEQUENCE 132 AA; 14890 MW; DA27A3A55C4A6B5A CRC64;
MSNDTPFDAL WQRMLARGWT PVSESRLDDW LTQAPDGVVL LSSDPKRTPE VSDNPVMIGE
LLREFPDYTW QVAIADLEQS EAIGDRFGVF RFPATLVFTG GNYRGVLNGI HPWAELINLM
RGLVEPQQER AS
