HYBF_SALTY
ID HYBF_SALTY Reviewed; 113 AA.
AC P64421; Q8XEP6;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Hydrogenase maturation factor HybF {ECO:0000255|HAMAP-Rule:MF_02099};
GN Name=hybF {ECO:0000255|HAMAP-Rule:MF_02099}; OrderedLocusNames=STM3144;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Involved in the maturation of [NiFe] hydrogenases. Required
CC for nickel insertion into the metal center of the hydrogenase.
CC {ECO:0000255|HAMAP-Rule:MF_02099}.
CC -!- SIMILARITY: Belongs to the HypA/HybF family. HybF subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_02099}.
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DR EMBL; AE006468; AAL22018.1; -; Genomic_DNA.
DR RefSeq; NP_462059.1; NC_003197.2.
DR RefSeq; WP_000544945.1; NC_003197.2.
DR AlphaFoldDB; P64421; -.
DR SMR; P64421; -.
DR STRING; 99287.STM3144; -.
DR PaxDb; P64421; -.
DR EnsemblBacteria; AAL22018; AAL22018; STM3144.
DR GeneID; 1254667; -.
DR GeneID; 66757450; -.
DR KEGG; stm:STM3144; -.
DR PATRIC; fig|99287.12.peg.3332; -.
DR HOGENOM; CLU_126929_0_0_6; -.
DR OMA; ILLCPCG; -.
DR PhylomeDB; P64421; -.
DR BioCyc; SENT99287:STM3144-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016151; F:nickel cation binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR GO; GO:0051604; P:protein maturation; IBA:GO_Central.
DR HAMAP; MF_02099; HybF_subfam; 1.
DR HAMAP; MF_00213; HypA_HybF; 1.
DR InterPro; IPR039002; HybF.
DR InterPro; IPR020538; Hydgase_Ni_incorp_HypA/HybF_CS.
DR InterPro; IPR000688; HypA/HybF.
DR PANTHER; PTHR34535; PTHR34535; 1.
DR Pfam; PF01155; HypA; 1.
DR PIRSF; PIRSF004761; Hydrgn_mat_HypA; 1.
DR TIGRFAMs; TIGR00100; hypA; 1.
DR PROSITE; PS01249; HYPA; 1.
PE 3: Inferred from homology;
KW Metal-binding; Nickel; Reference proteome; Zinc.
FT CHAIN 1..113
FT /note="Hydrogenase maturation factor HybF"
FT /id="PRO_0000129070"
FT BINDING 2
FT /ligand="Ni(2+)"
FT /ligand_id="ChEBI:CHEBI:49786"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02099"
FT BINDING 3
FT /ligand="Ni(2+)"
FT /ligand_id="ChEBI:CHEBI:49786"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02099"
FT BINDING 73
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02099"
FT BINDING 76
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02099"
FT BINDING 89
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02099"
FT BINDING 92
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02099"
SQ SEQUENCE 113 AA; 12659 MW; F3294A66483A7DCA CRC64;
MHELSLCQSA VEIIQQQAEQ HGVARVTGVW LEIGALSCVE ERAVRFSFDI ACQGTLAQGC
ELHIDYRPAQ AWCWDCSQVV EILRHDAQCP HCHGDRLRVD TGDSLKVKSI EVE
