ID   HYBG_SHIFL              Reviewed;          82 AA.
AC   P0AAN0; P37185;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Hydrogenase maturation factor HybG {ECO:0000250|UniProtKB:P0AAM7};
GN   Name=hybG; OrderedLocusNames=SF3037, S3238;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Involved in the maturation of [NiFe] hydrogenases. Involved
CC       in the biosynthesis of the Fe(CN)(2)CO cofactor. HybG delivers iron-
CC       bound CO(2) to HypD where reduction to CO probably occurs. In complex
CC       with HypD, accepts the cyanide ligand generated by HypF and HypE, and
CC       also coordinates the carbon monoxide ligand.
CC       {ECO:0000250|UniProtKB:P0AAM7}.
CC   -!- PATHWAY: Protein modification; [NiFe] hydrogenase maturation.
CC       {ECO:0000250|UniProtKB:P0AAM7}.
CC   -!- SIMILARITY: Belongs to the HupF/HypC family. {ECO:0000305}.
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DR   EMBL; AE005674; AAN44515.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP18326.1; -; Genomic_DNA.
DR   RefSeq; NP_708808.1; NC_004337.2.
DR   RefSeq; WP_000334896.1; NZ_WPGW01000034.1.
DR   AlphaFoldDB; P0AAN0; -.
DR   SMR; P0AAN0; -.
DR   STRING; 198214.SF3037; -.
DR   EnsemblBacteria; AAN44515; AAN44515; SF3037.
DR   EnsemblBacteria; AAP18326; AAP18326; S3238.
DR   GeneID; 1026635; -.
DR   GeneID; 67415062; -.
DR   KEGG; sfl:SF3037; -.
DR   KEGG; sfx:S3238; -.
DR   PATRIC; fig|198214.7.peg.3611; -.
DR   HOGENOM; CLU_159381_1_1_6; -.
DR   OMA; HYPARVD; -.
DR   OrthoDB; 2031925at2; -.
DR   UniPathway; UPA00335; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   InterPro; IPR019812; Hydgase_assmbl_chp_CS.
DR   InterPro; IPR001109; Hydrogenase_HupF/HypC.
DR   PANTHER; PTHR35177; PTHR35177; 1.
DR   Pfam; PF01455; HupF_HypC; 1.
DR   PRINTS; PR00445; HUPFHYPC.
DR   TIGRFAMs; TIGR00074; hypC_hupF; 1.
DR   PROSITE; PS01097; HUPF_HYPC; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..82
FT                   /note="Hydrogenase maturation factor HybG"
FT                   /id="PRO_0000201406"
FT   SITE            2
FT                   /note="Important for interaction with HypD and the
FT                   precursor form of hydrogenase"
FT                   /evidence="ECO:0000250|UniProtKB:P0AAM3"
SQ   SEQUENCE   82 AA;  8808 MW;  8E9736BFC4EFD626 CRC64;
     MCIGVPGQVL AVGEDIHQLA QVEVCGIKRD VNIALICEGN PADLLGQWVL VHVGFAMSII
     DEDEAKATLD ALRQMDYDIT SA