ID   HYCH_ECOLI              Reviewed;         136 AA.
AC   P0AEV7; P16434; Q2MAB1;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Formate hydrogenlyase maturation protein HycH;
GN   Name=hycH; Synonyms=hevH; OrderedLocusNames=b2718, JW2688;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12 / MC4100 / ATCC 35695 / DSM 6574;
RX   PubMed=2187144; DOI=10.1111/j.1365-2958.1990.tb00590.x;
RA   Boehm R., Sauter M., Boeck A.;
RT   "Nucleotide sequence and expression of an operon in Escherichia coli coding
RT   for formate hydrogenlyase components.";
RL   Mol. Microbiol. 4:231-243(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 130-136.
RC   STRAIN=K12 / MC4100 / ATCC 35695 / DSM 6574;
RX   PubMed=7851435; DOI=10.1111/j.1432-1033.1995.tb20422.x;
RA   Rossmann R., Maier T., Lottspeich F., Boeck A.;
RT   "Characterisation of a protease from Escherichia coli involved in
RT   hydrogenase maturation.";
RL   Eur. J. Biochem. 227:545-550(1995).
RN   [5]
RP   FUNCTION.
RX   PubMed=1625581; DOI=10.1111/j.1365-2958.1992.tb00873.x;
RA   Sauter M., Boehm R., Boeck A.;
RT   "Mutational analysis of the operon (hyc) determining hydrogenase 3
RT   formation in Escherichia coli.";
RL   Mol. Microbiol. 6:1523-1532(1992).
CC   -!- FUNCTION: Seems to be required for the conversion of a precursor form
CC       of the large subunit of hydrogenlyase (HycE) into a mature form.
CC       {ECO:0000269|PubMed:1625581}.
CC   -!- SIMILARITY: To E.coli HyfJ. {ECO:0000305}.
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DR   EMBL; X17506; CAA35553.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; U29579; AAA69228.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC75760.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76795.1; -; Genomic_DNA.
DR   PIR; S08626; S08626.
DR   RefSeq; NP_417198.1; NC_000913.3.
DR   RefSeq; WP_001291921.1; NZ_STEB01000027.1.
DR   AlphaFoldDB; P0AEV7; -.
DR   BioGRID; 4262938; 20.
DR   IntAct; P0AEV7; 2.
DR   STRING; 511145.b2718; -.
DR   PaxDb; P0AEV7; -.
DR   PRIDE; P0AEV7; -.
DR   EnsemblBacteria; AAC75760; AAC75760; b2718.
DR   EnsemblBacteria; BAE76795; BAE76795; BAE76795.
DR   GeneID; 66673413; -.
DR   GeneID; 947438; -.
DR   KEGG; ecj:JW2688; -.
DR   KEGG; eco:b2718; -.
DR   PATRIC; fig|1411691.4.peg.4023; -.
DR   EchoBASE; EB0476; -.
DR   eggNOG; ENOG502ZBMB; Bacteria.
DR   HOGENOM; CLU_121340_0_0_6; -.
DR   OMA; YLMVRRH; -.
DR   PhylomeDB; P0AEV7; -.
DR   BioCyc; EcoCyc:EG10481-MON; -.
DR   PRO; PR:P0AEV7; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0065003; P:protein-containing complex assembly; IDA:EcoCyc.
DR   InterPro; IPR010005; Formate_DH_maturation_HycH.
DR   Pfam; PF07450; HycH; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..136
FT                   /note="Formate hydrogenlyase maturation protein HycH"
FT                   /id="PRO_0000084103"
SQ   SEQUENCE   136 AA;  15465 MW;  F98F81AA5A211393 CRC64;
     MSEKVVFSQL SRKFIDENDA TPAEAQQVVY YSLAIGHHLG VIDCLEAALT CPWDEYLAWI
     ATLEAGSEAR RKMEGVPKYG EIVIDINHVP MLANAFDKAR AAQTSQQQEW STMLLSMLHD
     IHQENAIYLM VRRLRD