ID   HYP1_DAVTA              Reviewed;         105 AA.
AC   Q8NIN9;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Hydrophobin-1;
DE   AltName: Allergen=Cla h ?;
DE   Flags: Precursor;
GN   Name=HCh-1;
OS   Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Cladosporiales; Cladosporiaceae; Cladosporium.
OX   NCBI_TaxID=29918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND ALLERGEN.
RC   STRAIN=280202-Berlin;
RX   PubMed=12534552; DOI=10.1046/j.1365-2222.2003.01574.x;
RA   Weichel M., Schmid-Grendelmeier P., Rhyner C., Achatz G., Blaser K.,
RA   Crameri R.;
RT   "IgE-binding and skin test reactivity to hydrophobin HCh-1 from
RT   Cladosporium herbarum, the first allergenic cell wall component of fungi.";
RL   Clin. Exp. Allergy 33:72-77(2003).
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000250}.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE.
CC       {ECO:0000269|PubMed:12534552}.
CC   -!- SIMILARITY: Belongs to the fungal hydrophobin family. {ECO:0000305}.
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DR   EMBL; AJ496190; CAD42710.1; -; mRNA.
DR   AlphaFoldDB; Q8NIN9; -.
DR   Allergome; 834; Cla h HCh1.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Allergen; Cell wall; Disulfide bond; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..105
FT                   /note="Hydrophobin-1"
FT                   /id="PRO_5000068672"
FT   DISULFID        42..83
FT                   /evidence="ECO:0000250"
FT   DISULFID        50..76
FT                   /evidence="ECO:0000250"
FT   DISULFID        51..62
FT                   /evidence="ECO:0000250"
FT   DISULFID        84..100
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   105 AA;  10532 MW;  9363A8ED537B9311 CRC64;
     MAFIKSLLIA SVAAVAFAAP QGGASDNNKK VEIDGQDSAP VCGNGQKVAC CNSGEDLIGL
     NCLSIPILAI PIQKACGSNI AACCQTGDSE GNLLNLEANC LAIPL